276506

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RelB
Location 113868..114466 Replicon plasmid pCB3126_1
Accession NZ_CP121660
Organism Sinorhizobium terangae strain CB3126

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag QA637_RS19255 Protein ID WP_153441353.1
Coordinates 114173..114466 (+) Length 98 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID Q930F1
Locus tag QA637_RS19250 Protein ID WP_010967242.1
Coordinates 113868..114176 (+) Length 103 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QA637_RS19230 (QA637_19230) 110900..111934 + 1035 WP_283066277.1 ABC transporter substrate-binding protein -
QA637_RS19235 (QA637_19235) 112226..112453 + 228 Protein_106 hypothetical protein -
QA637_RS19240 (QA637_19240) 112607..112927 + 321 WP_283066278.1 hypothetical protein -
QA637_RS19245 (QA637_19245) 113219..113446 + 228 Protein_108 hypothetical protein -
QA637_RS19250 (QA637_19250) 113868..114176 + 309 WP_010967242.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
QA637_RS19255 (QA637_19255) 114173..114466 + 294 WP_153441353.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QA637_RS19260 (QA637_19260) 114821..115276 - 456 WP_153441354.1 DUF4440 domain-containing protein -
QA637_RS19265 (QA637_19265) 115815..116852 + 1038 WP_283066298.1 IS110 family transposase -
QA637_RS19270 (QA637_19270) 117399..119033 - 1635 WP_283066299.1 ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Conjugative plasmid - htpB / katA 1..2093508 2093508


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-90)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-53)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11278.93 Da        Isoelectric Point: 6.4734

>T276506 WP_153441353.1 NZ_CP121660:114173-114466 [Sinorhizobium terangae]
MRLVWARYALDDRDTIFSYIERENPRAAVHVDEEIVSAVRRLLDFPESGRPGRVAGTRELVIPRTPYIAAYMVMADRIRI
LRVLHGAQKWPSELDDE

Download         Length: 294 bp

Antitoxin


Download         Length: 103 a.a.        Molecular weight: 11210.58 Da        Isoelectric Point: 5.6604

>AT276506 WP_010967242.1 NZ_CP121660:113868-114176 [Sinorhizobium terangae]
MASNALVQTRIDAEVKERATAVLENMGLTVSDAVRILLTRTANEGALPLELFSHSEAHDAWFRAKVLRALEDTRPDVDDA
DADAHFRERRAAALRKAAAGDR

Download         Length: 309 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB Q930F1

References