Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC(toxin)
Location 10005..10648 Replicon plasmid pCB3171_4
Accession NZ_CP121656
Organism Rhizobium sp. CB3171

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag QA648_RS35520 Protein ID WP_283055014.1
Coordinates 10005..10391 (-) Length 129 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag QA648_RS35525 Protein ID WP_283055015.1
Coordinates 10391..10648 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QA648_RS35495 (QA648_35495) 5096..6193 + 1098 WP_283055071.1 IS1595 family transposase -
QA648_RS35500 (QA648_35500) 6458..7279 - 822 WP_283055010.1 hypothetical protein -
QA648_RS35505 (QA648_35505) 7808..8266 + 459 WP_283055011.1 GNAT family N-acetyltransferase -
QA648_RS35510 (QA648_35510) 8558..8794 + 237 WP_283055012.1 hypothetical protein -
QA648_RS35515 (QA648_35515) 8953..10005 - 1053 WP_283055013.1 site-specific integrase -
QA648_RS35520 (QA648_35520) 10005..10391 - 387 WP_283055014.1 type II toxin-antitoxin system VapC family toxin Toxin
QA648_RS35525 (QA648_35525) 10391..10648 - 258 WP_283055015.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
QA648_RS35530 (QA648_35530) 10909..12480 + 1572 WP_283055072.1 Mu transposase C-terminal domain-containing protein -
QA648_RS35535 (QA648_35535) 12471..13409 + 939 WP_283055016.1 TniB family NTP-binding protein -
QA648_RS35540 (QA648_35540) 13406..14548 + 1143 WP_283055017.1 TniQ family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..186301 186301
- flank IS/Tn - - 5096..6193 1097


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(1-124)

Antitoxin

Antitoxin VapB-like

(2-84)


Sequences

Toxin        


Download         Length: 129 a.a.        Molecular weight: 14094.36 Da        Isoelectric Point: 4.4937

>T276504 WP_283055014.1 NZ_CP121656:c10391-10005 [Rhizobium sp. CB3171]
MVIDTSAIVAMLRNEPEMERLEKALVADPIRLVPATCVLEARMVLVSRRGEHALAEIDLWLSKIKAEIIPVDADLVDLAT
QAWLTYGKGRHPAGLNFADCFSYALAKRADEALLFIGQDFAQTDIEAA

Download         Length: 387 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9346.47 Da        Isoelectric Point: 6.0692

>AT276504 WP_283055015.1 NZ_CP121656:c10648-10391 [Rhizobium sp. CB3171]
VSLNIKNPATVALVDELARRQGISKTAAIHQALSEQLRRMGHGGGAQERLLHELQAIRQRVAHLPELDSRSDEDIVGYDE
DGIPN

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References