Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 4027..4632 Replicon plasmid pCB3171_3
Accession NZ_CP121655
Organism Rhizobium sp. CB3171

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag QA648_RS34445 Protein ID WP_283054928.1
Coordinates 4336..4632 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag QA648_RS34440 Protein ID WP_283054868.1
Coordinates 4027..4332 (-) Length 102 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QA648_RS34420 (QA648_34420) 1..1197 + 1197 WP_283054863.1 plasmid partitioning protein RepA -
QA648_RS34425 (QA648_34425) 1201..2211 + 1011 WP_283054865.1 plasmid partitioning protein RepB -
QA648_RS34430 (QA648_34430) 2366..3586 + 1221 WP_283054866.1 plasmid replication protein RepC -
QA648_RS34435 (QA648_34435) 3654..3899 + 246 WP_283054867.1 helix-turn-helix transcriptional regulator -
QA648_RS34440 (QA648_34440) 4027..4332 - 306 WP_283054868.1 putative addiction module antidote protein Antitoxin
QA648_RS34445 (QA648_34445) 4336..4632 - 297 WP_283054928.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QA648_RS34450 (QA648_34450) 4833..5750 - 918 WP_283054929.1 recombinase family protein -
QA648_RS34455 (QA648_34455) 6156..6540 - 385 Protein_7 IS630 family transposase -
QA648_RS34460 (QA648_34460) 6680..7264 - 585 WP_283054869.1 TetR/AcrR family transcriptional regulator -
QA648_RS34465 (QA648_34465) 7953..8702 + 750 WP_283054930.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..212457 212457


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(16-90)

Antitoxin

Uncharacterized protein HI1420

(4-91)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11047.80 Da        Isoelectric Point: 10.4457

>T276502 WP_283054928.1 NZ_CP121655:c4632-4336 [Rhizobium sp. CB3171]
MFSIRETVEFSNWMLRLRDDRAKARIGQRIMRLASGNAGDVKPVGEGVSELRINYGPGYRVYFVREGSIMIVLLCGGDKK
TQSRDIERAKALANALKE

Download         Length: 297 bp

Antitoxin


Download         Length: 102 a.a.        Molecular weight: 10716.16 Da        Isoelectric Point: 4.8605

>AT276502 WP_283054868.1 NZ_CP121655:c4332-4027 [Rhizobium sp. CB3171]
MTLKTREFDPARYLDSEDAIDEYILAASESGDPHELAAALGVVAKARGITEVARKSGLTRQAIYKALDEDGNPELGTIAR
VADALGFKLSLVPKSAITKAA

Download         Length: 306 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References