Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 2735900..2736669 Replicon plasmid pCB3171_1
Accession NZ_CP121653
Organism Rhizobium sp. CB3171

Toxin (Protein)


Gene name TacT2 Uniprot ID -
Locus tag QA648_RS31575 Protein ID WP_283052914.1
Coordinates 2735900..2736394 (-) Length 165 a.a.

Antitoxin (Protein)


Gene name tacA Uniprot ID -
Locus tag QA648_RS31580 Protein ID WP_283054321.1
Coordinates 2736391..2736669 (-) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QA648_RS31565 (QA648_31565) 2732561..2734186 - 1626 WP_283052912.1 winged helix-turn-helix domain-containing protein -
QA648_RS31570 (QA648_31570) 2734488..2735414 + 927 WP_283052913.1 hypothetical protein -
QA648_RS31575 (QA648_31575) 2735900..2736394 - 495 WP_283052914.1 GNAT family N-acetyltransferase Toxin
QA648_RS31580 (QA648_31580) 2736391..2736669 - 279 WP_283054321.1 DUF1778 domain-containing protein Antitoxin
QA648_RS31585 (QA648_31585) 2736753..2737190 + 438 WP_283052916.1 curlin -
QA648_RS31590 (QA648_31590) 2737256..2737654 + 399 WP_283052918.1 curli-like amyloid fiber formation chaperone CsgH -
QA648_RS31595 (QA648_31595) 2737829..2738242 + 414 WP_283052920.1 curlin -
QA648_RS31600 (QA648_31600) 2738737..2740083 - 1347 WP_283052921.1 FAD-binding oxidoreductase -
QA648_RS31605 (QA648_31605) 2740080..2741597 - 1518 WP_260304528.1 aldehyde dehydrogenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - katA / ddhA / icl 1..2831118 2831118


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(43-141)

Antitoxin

Vibrio phage ICP1, Orf50

(18-84)


Sequences

Toxin        


Download         Length: 165 a.a.        Molecular weight: 17710.25 Da        Isoelectric Point: 8.0293

>T276500 WP_283052914.1 NZ_CP121653:c2736394-2735900 [Rhizobium sp. CB3171]
VTLSAPAPLADHHELAEFNSGVPELDDWLRRRARSNQAGGARTFVVCEGSRVIAYYALASGAVRQPEAPGRFRRNMPDPI
PVAVLGRLAIDQSYQGRGFGRALVRDAGLRLLNAAEILGIRGVLVPAISDDARAFYEAVGFLSFPSDPMMRMVGLPDLNN
ALNP

Download         Length: 495 bp

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10621.09 Da        Isoelectric Point: 8.5607

>AT276500 WP_283054321.1 NZ_CP121653:c2736669-2736391 [Rhizobium sp. CB3171]
IQSGFIRKDRSPLKPRTTRNLIDRAAELLGKTRTDFILEASERRAEEMLPDRTIFTVSPEIYAEYLARLDAPAQLNERLT
RTMSTKAPWDEA

Download         Length: 279 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References