Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/LOTUS_5_Limkain_b1-Phd
Location 1359079..1359761 Replicon plasmid pCB3171_1
Accession NZ_CP121653
Organism Rhizobium sp. CB3171

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag QA648_RS25610 Protein ID WP_283054192.1
Coordinates 1359339..1359761 (+) Length 141 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag QA648_RS25605 Protein ID WP_104826582.1
Coordinates 1359079..1359342 (+) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QA648_RS25590 (QA648_25590) 1354164..1354880 - 717 WP_104826585.1 GntR family transcriptional regulator -
QA648_RS25595 (QA648_25595) 1355482..1357755 + 2274 WP_283054190.1 cation:proton antiporter -
QA648_RS25600 (QA648_25600) 1357866..1358966 + 1101 WP_283054191.1 YihY/virulence factor BrkB family protein -
QA648_RS25605 (QA648_25605) 1359079..1359342 + 264 WP_104826582.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
QA648_RS25610 (QA648_25610) 1359339..1359761 + 423 WP_283054192.1 type II toxin-antitoxin system VapC family toxin Toxin
QA648_RS25615 (QA648_25615) 1359842..1361917 - 2076 WP_283054193.1 glycogen debranching protein GlgX -
QA648_RS25620 (QA648_25620) 1362007..1364493 - 2487 WP_283054270.1 malto-oligosyltrehalose synthase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - katA / ddhA / icl 1..2831118 2831118


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-123)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(8-58)


Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 15561.89 Da        Isoelectric Point: 5.6799

>T276499 WP_283054192.1 NZ_CP121653:1359339-1359761 [Rhizobium sp. CB3171]
VRLLLDTNVLSEVTRPRPDAHVLKWLDGLDEDRSFISVVSIAEIRRGVALMDSGRKRDALTEWLAQDLPQRFEHRVLPVN
EPVAVAWGDLMGLAKRNGRGLSSMDGLIAATAIAHNLALATRNIRDFEGFGIELVDPWVV

Download         Length: 423 bp

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9630.90 Da        Isoelectric Point: 8.0256

>AT276499 WP_104826582.1 NZ_CP121653:1359079-1359342 [Rhizobium sp. CB3171]
MRPTPSEQNWTVASAKAKLSEVIECAQSAPQTITRNGKPSVVVVSAEEWHRKTARKGTLAEFLMGSPLRGADLDLERQRD
DPRDLSL

Download         Length: 264 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References