Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 3955064..3955707 Replicon chromosome
Accession NZ_CP121652
Organism Rhizobium sp. CB3171

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag QA648_RS19250 Protein ID WP_283048779.1
Coordinates 3955064..3955468 (-) Length 135 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag QA648_RS19255 Protein ID WP_104821787.1
Coordinates 3955465..3955707 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QA648_RS19215 (QA648_19215) 3950161..3951066 + 906 WP_283048768.1 LysR family transcriptional regulator -
QA648_RS19220 (QA648_19220) 3951067..3951942 - 876 WP_104821780.1 LysR family transcriptional regulator -
QA648_RS19225 (QA648_19225) 3952039..3953322 + 1284 WP_283048771.1 MFS transporter -
QA648_RS19230 (QA648_19230) 3953345..3953731 + 387 WP_283048773.1 VOC family protein -
QA648_RS19235 (QA648_19235) 3953850..3954191 + 342 WP_283048775.1 metalloregulator ArsR/SmtB family transcription factor -
QA648_RS19240 (QA648_19240) 3954175..3954657 + 483 WP_283048777.1 SRPBCC domain-containing protein -
QA648_RS19245 (QA648_19245) 3954663..3955067 + 405 WP_104821785.1 GFA family protein -
QA648_RS19250 (QA648_19250) 3955064..3955468 - 405 WP_283048779.1 type II toxin-antitoxin system VapC family toxin Toxin
QA648_RS19255 (QA648_19255) 3955465..3955707 - 243 WP_104821787.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
QA648_RS19260 (QA648_19260) 3955773..3956447 - 675 WP_104821788.1 hypothetical protein -
QA648_RS19265 (QA648_19265) 3956574..3958235 - 1662 WP_283048782.1 urocanate hydratase -
QA648_RS19270 (QA648_19270) 3958278..3958607 - 330 WP_283048784.1 TfoX/Sxy family protein -
QA648_RS19275 (QA648_19275) 3958626..3959726 - 1101 WP_283048785.1 DUF917 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-122)

Antitoxin

SpoVT-AbrB domain

(7-44)


Sequences

Toxin        


Download         Length: 135 a.a.        Molecular weight: 15083.21 Da        Isoelectric Point: 6.4885

>T276498 WP_283048779.1 NZ_CP121652:c3955468-3955064 [Rhizobium sp. CB3171]
VKYLLDSNAVIALMKGHTGFVSELRRHKPQDFAISAIVAHELFYGAYKGQRVADNLVRVDALQFETLDFDREDARVVGEI
RANLASLGTPIGAYDVLIAGQAVARDLILITRNVREFERVHKLRFEDWESLPSS

Download         Length: 405 bp

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9337.45 Da        Isoelectric Point: 4.3430

>AT276498 WP_104821787.1 NZ_CP121652:c3955707-3955465 [Rhizobium sp. CB3171]
MDTAKIFWSGRSQAIRLPKEFRLDGEEVRIRRQGKAIILEPIAEDWDWLESVTGPVDHDFEEAATEQPAEQQRPELDIFK

Download         Length: 243 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References