276497

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ParE-CopA/RHH(antitoxin)
Location 3754185..3754750 Replicon chromosome
Accession NZ_CP121652
Organism Rhizobium sp. CB3171

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag QA648_RS18235 Protein ID WP_283051410.1
Coordinates 3754505..3754750 (+) Length 82 a.a.

Antitoxin (Protein)


Gene name copA Uniprot ID -
Locus tag QA648_RS18230 Protein ID WP_104821613.1
Coordinates 3754185..3754469 (+) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QA648_RS18210 (QA648_18210) 3749638..3751275 + 1638 WP_283048514.1 ABC transporter ATP-binding protein -
QA648_RS18215 (QA648_18215) 3751288..3752247 + 960 WP_283048515.1 glyoxylate/hydroxypyruvate reductase A -
QA648_RS18220 (QA648_18220) 3752325..3752594 + 270 WP_283048517.1 hypothetical protein -
QA648_RS18225 (QA648_18225) 3752793..3754097 + 1305 WP_104821612.1 nicotinate phosphoribosyltransferase -
QA648_RS18230 (QA648_18230) 3754185..3754469 + 285 WP_104821613.1 CopG family transcriptional regulator Antitoxin
QA648_RS18235 (QA648_18235) 3754505..3754750 + 246 WP_283051410.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QA648_RS18240 (QA648_18240) 3754758..3755723 - 966 WP_283051412.1 hypothetical protein -
QA648_RS18245 (QA648_18245) 3755888..3758050 + 2163 WP_104821615.1 mechanosensitive ion channel family protein -
QA648_RS18250 (QA648_18250) 3758148..3759176 + 1029 WP_283048520.1 aldo/keto reductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-78)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 82 a.a.        Molecular weight: 9037.38 Da        Isoelectric Point: 9.9332

>T276497 WP_283051410.1 NZ_CP121652:3754505-3754750 [Rhizobium sp. CB3171]
MRAFLRSKNAAAARKASARIIQTIQILSSQPDMGRPVEGSEQGLRELIVTFGRDGYIVLYQYLGEDVLIAAIRHGREDGY
K

Download         Length: 246 bp

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10888.04 Da        Isoelectric Point: 4.7881

>AT276497 WP_104821613.1 NZ_CP121652:3754185-3754469 [Rhizobium sp. CB3171]
MSPALKASVEIDPDVNERLEKLAASRHRHPNRLLNEAVRQYVEREEKRDSLLQDVRRSLDDYQATGLHVTGDEVIAWLET
WGDDDEKAPPECHR

Download         Length: 285 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References