Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hicAB/-
Location 3201376..3201983 Replicon chromosome
Accession NZ_CP121652
Organism Rhizobium sp. CB3171

Toxin (Protein)


Gene name hicA Uniprot ID -
Locus tag QA648_RS15640 Protein ID WP_283047908.1
Coordinates 3201376..3201630 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name hicB Uniprot ID -
Locus tag QA648_RS15645 Protein ID WP_283047909.1
Coordinates 3201627..3201983 (+) Length 119 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QA648_RS15610 (QA648_15610) 3196575..3197231 - 657 WP_104824704.1 response regulator transcription factor -
QA648_RS15615 (QA648_15615) 3197471..3197755 + 285 WP_104824705.1 hypothetical protein -
QA648_RS15620 (QA648_15620) 3197819..3199234 - 1416 WP_283047905.1 PLP-dependent aminotransferase family protein -
QA648_RS15625 (QA648_15625) 3199341..3200204 + 864 WP_283047906.1 DMT family transporter -
QA648_RS15630 (QA648_15630) 3200287..3200751 + 465 WP_104824707.1 nuclear transport factor 2 family protein -
QA648_RS15635 (QA648_15635) 3200756..3201319 + 564 WP_283047907.1 TetR/AcrR family transcriptional regulator -
QA648_RS15640 (QA648_15640) 3201376..3201630 + 255 WP_283047908.1 type II toxin-antitoxin system HicA family toxin Toxin
QA648_RS15645 (QA648_15645) 3201627..3201983 + 357 WP_283047909.1 type II toxin-antitoxin system HicB family antitoxin Antitoxin
QA648_RS15650 (QA648_15650) 3202055..3202618 - 564 WP_283047910.1 hypothetical protein -
QA648_RS15655 (QA648_15655) 3202735..3203370 + 636 WP_283047912.1 TetR-like C-terminal domain-containing protein -
QA648_RS15660 (QA648_15660) 3203528..3204853 + 1326 WP_283047914.1 glucoamylase family protein -
QA648_RS15665 (QA648_15665) 3204904..3205893 - 990 WP_283051362.1 Ldh family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HicA mRNA interferase family

(23-81)

Antitoxin

Uncharacterised protein family HicB

(54-104)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 9293.58 Da        Isoelectric Point: 9.9233

>T276496 WP_283047908.1 NZ_CP121652:3201376-3201630 [Rhizobium sp. CB3171]
MNSKQIRTLAAVFRNPVSGTIDWADIESLLIATGANIIEGSGSRVKFEKDGAVASFHRPHPDKEAKRYQVRDAREFLIQI
GVTP

Download         Length: 255 bp

Antitoxin


Download         Length: 119 a.a.        Molecular weight: 13207.82 Da        Isoelectric Point: 6.3331

>AT276496 WP_283047909.1 NZ_CP121652:3201627-3201983 [Rhizobium sp. CB3171]
VNTMSYKSYHARIEYDDEDEIFFGKIAGISDVIGFHAESVAELKSAFHEAVDDYIATCHRIGKEPQKPYSGKMMFRVDPE
VHRRAAMAAELSGKSLNQWAEEALEKAAKQAGQTRRAG

Download         Length: 357 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References