Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/Phd-VapC
Location 2407979..2408643 Replicon chromosome
Accession NZ_CP121652
Organism Rhizobium sp. CB3171

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag QA648_RS11835 Protein ID WP_104824050.1
Coordinates 2407979..2408233 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag QA648_RS11840 Protein ID WP_260303102.1
Coordinates 2408233..2408643 (+) Length 137 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QA648_RS11805 (QA648_11805) 2403491..2404072 + 582 WP_283047072.1 NAD(P)H-dependent oxidoreductase -
QA648_RS11810 (QA648_11810) 2404117..2404506 - 390 WP_283047073.1 RidA family protein -
QA648_RS11815 (QA648_11815) 2404619..2405515 - 897 WP_283047075.1 DMT family transporter -
QA648_RS11820 (QA648_11820) 2405715..2406161 + 447 WP_283047077.1 hypothetical protein -
QA648_RS11825 (QA648_11825) 2406183..2406800 - 618 WP_104824048.1 alpha/beta hydrolase -
QA648_RS11830 (QA648_11830) 2406814..2407746 - 933 WP_104824049.1 VOC family protein -
QA648_RS11835 (QA648_11835) 2407979..2408233 + 255 WP_104824050.1 type II toxin-antitoxin system Phd/YefM family antitoxin Toxin
QA648_RS11840 (QA648_11840) 2408233..2408643 + 411 WP_260303102.1 type II toxin-antitoxin system VapC family toxin Antitoxin
QA648_RS11845 (QA648_11845) 2408637..2409338 - 702 WP_283047081.1 uracil-DNA glycosylase -
QA648_RS11850 (QA648_11850) 2409428..2410069 - 642 WP_283051315.1 septation protein IspZ -
QA648_RS11855 (QA648_11855) 2410157..2412604 - 2448 WP_283047083.1 FAD-dependent oxidoreductase -
QA648_RS11860 (QA648_11860) 2412614..2413492 - 879 WP_283047085.1 choline kinase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(3-63)

Antitoxin

PIN domain

(2-116)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 9216.26 Da        Isoelectric Point: 4.4165

>T276494 WP_104824050.1 NZ_CP121652:2407979-2408233 [Rhizobium sp. CB3171]
MDWPLQDAKNQFSKVVQKARSEGPQTVTLRGERAVVVLSAEDYDALRAGKPSLVDDLLSGPAWDDELADAVTTRDKTPSR
DVAF

Download         Length: 255 bp

Antitoxin


Download         Length: 137 a.a.        Molecular weight: 15182.37 Da        Isoelectric Point: 6.4860

>AT276494 WP_260303102.1 NZ_CP121652:2408233-2408643 [Rhizobium sp. CB3171]
MYLIDTNIISEARRGTIEAISWLRIADPSTVYLSVITLGEVMRGIALKRRTDPRAAAHLEEWLRKLRHDHSGRILPITDQ
IAVEWGRISALRPRGDADGLIAATAIVHDLIIVTRNVSDFDDAGVSVINPWDQASY

Download         Length: 411 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References