Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VapB
Location 739236..739795 Replicon chromosome
Accession NZ_CP121652
Organism Rhizobium sp. CB3171

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag QA648_RS03640 Protein ID WP_283049680.1
Coordinates 739236..739601 (-) Length 122 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag QA648_RS03645 Protein ID WP_104822467.1
Coordinates 739598..739795 (-) Length 66 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QA648_RS03620 (QA648_03620) 734273..735517 - 1245 WP_283049673.1 efflux RND transporter periplasmic adaptor subunit -
QA648_RS03625 (QA648_03625) 735949..736737 - 789 WP_283049675.1 SDR family oxidoreductase -
QA648_RS03630 (QA648_03630) 737023..738687 + 1665 WP_283049677.1 electron transfer flavoprotein-ubiquinone oxidoreductase -
QA648_RS03635 (QA648_03635) 738756..739220 + 465 WP_283049678.1 GNAT family N-acetyltransferase -
QA648_RS03640 (QA648_03640) 739236..739601 - 366 WP_283049680.1 PIN domain-containing protein Toxin
QA648_RS03645 (QA648_03645) 739598..739795 - 198 WP_104822467.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
QA648_RS03650 (QA648_03650) 739898..740800 - 903 WP_283049682.1 DMT family transporter -
QA648_RS03655 (QA648_03655) 740946..741419 + 474 WP_104822469.1 Lrp/AsnC family transcriptional regulator -
QA648_RS03660 (QA648_03660) 741470..742843 - 1374 WP_104822470.1 magnesium transporter -
QA648_RS03665 (QA648_03665) 743042..743230 - 189 WP_283049683.1 hypothetical protein -
QA648_RS03670 (QA648_03670) 743241..744449 - 1209 WP_283051205.1 MFS transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-113)

Antitoxin

Bacterial antitoxin of type II TA system, VapB

(1-47)


Sequences

Toxin        


Download         Length: 122 a.a.        Molecular weight: 13770.07 Da        Isoelectric Point: 8.4792

>T276492 WP_283049680.1 NZ_CP121652:c739601-739236 [Rhizobium sp. CB3171]
MILVDTSIWIDHFHSLDAKLQSLLEQKQVLIHPVVIGEISLGNLRQYDLVMRSLSRLYQISKAPDDDVLYFIRSNRLQGM
GIGYVDAHLAAAAILTPGTYLWTRDKRLQRVAENLRIAALL

Download         Length: 366 bp

Antitoxin


Download         Length: 66 a.a.        Molecular weight: 7174.25 Da        Isoelectric Point: 5.0959

>AT276492 WP_104822467.1 NZ_CP121652:c739795-739598 [Rhizobium sp. CB3171]
MRTTVTIDDKLLADAREVTELAETSAIVREALKALIEREAARTLIRLGGTEPDIAAPPRRRFGVE

Download         Length: 198 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References