Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-dnstrm_HI1420
Location 606001..606578 Replicon chromosome
Accession NZ_CP121652
Organism Rhizobium sp. CB3171

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag QA648_RS02985 Protein ID WP_104822357.1
Coordinates 606288..606578 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag QA648_RS02980 Protein ID WP_104822356.1
Coordinates 606001..606285 (-) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QA648_RS02965 (QA648_02965) 602859..603857 + 999 WP_283049524.1 NAD(P)H-quinone oxidoreductase -
QA648_RS02970 (QA648_02970) 603838..605265 - 1428 WP_283049525.1 MFS transporter -
QA648_RS02975 (QA648_02975) 605367..605990 + 624 WP_283049526.1 MarR family transcriptional regulator -
QA648_RS02980 (QA648_02980) 606001..606285 - 285 WP_104822356.1 putative addiction module antidote protein Antitoxin
QA648_RS02985 (QA648_02985) 606288..606578 - 291 WP_104822357.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QA648_RS02990 (QA648_02990) 606758..607765 + 1008 WP_283049528.1 asparaginase -
QA648_RS02995 (QA648_02995) 607812..608573 - 762 WP_283049530.1 DeoR/GlpR family DNA-binding transcription regulator -
QA648_RS03000 (QA648_03000) 608696..609052 + 357 WP_283049532.1 DUF4406 domain-containing protein -
QA648_RS03005 (QA648_03005) 609189..609809 + 621 WP_283049534.1 glutathione S-transferase N-terminal domain-containing protein -
QA648_RS03010 (QA648_03010) 609810..610166 - 357 WP_283051197.1 MmcQ/YjbR family DNA-binding protein -
QA648_RS03015 (QA648_03015) 610285..610470 - 186 WP_283049536.1 hypothetical protein -
QA648_RS03020 (QA648_03020) 610618..611514 + 897 WP_104822362.1 LysR substrate-binding domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-95)

Antitoxin

Cro/C1-type helix-turn-helix domain

(46-90)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10666.35 Da        Isoelectric Point: 9.7931

>T276491 WP_104822357.1 NZ_CP121652:c606578-606288 [Rhizobium sp. CB3171]
MIEIRQTAEFAEWLGKIKDINAVARIQVRIRRLSLGNPGDVKPVGEGISELRIDYGPGYRLYYHKRGQELVLLLCGGDKS
TQNADIAKAKALAKEA

Download         Length: 291 bp

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 9883.22 Da        Isoelectric Point: 4.4488

>AT276491 WP_104822356.1 NZ_CP121652:c606285-606001 [Rhizobium sp. CB3171]
MALETKPWDPTEHLDSPEAIAAYVEAAFEDGDPALIAAVIGDVARARGMTQLAKEAGVSRETIYKAFSEGGNPTLETLSG
VIRALGLKLTVRAA

Download         Length: 285 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References