Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pasABC/RelE-HTH
Location 390828..391308 Replicon chromosome
Accession NZ_CP121652
Organism Rhizobium sp. CB3171

Toxin (Protein)


Gene name pasB Uniprot ID -
Locus tag QA648_RS01905 Protein ID WP_104822116.1
Coordinates 390828..391097 (-) Length 90 a.a.

Antitoxin (Protein)


Gene name pasA Uniprot ID -
Locus tag QA648_RS01910 Protein ID WP_104822117.1
Coordinates 391081..391308 (-) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QA648_RS01880 (QA648_01880) 386755..387804 + 1050 WP_283049292.1 aldo/keto reductase -
QA648_RS01885 (QA648_01885) 387850..388875 - 1026 WP_283051451.1 NAD(P)-dependent alcohol dehydrogenase -
QA648_RS01890 (QA648_01890) 388986..389888 + 903 WP_104822113.1 LysR family transcriptional regulator -
QA648_RS01895 (QA648_01895) 389889..390164 + 276 WP_104822114.1 LysR substrate-binding domain-containing protein -
QA648_RS01900 (QA648_01900) 390222..390770 - 549 WP_104822115.1 2'-5' RNA ligase family protein -
QA648_RS01905 (QA648_01905) 390828..391097 - 270 WP_104822116.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QA648_RS01910 (QA648_01910) 391081..391308 - 228 WP_104822117.1 DUF6290 family protein Antitoxin
QA648_RS01915 (QA648_01915) 391475..392998 + 1524 WP_104822118.1 histidine--tRNA ligase -
QA648_RS01920 (QA648_01920) 393155..394273 + 1119 WP_104822119.1 ATP phosphoribosyltransferase regulatory subunit -
QA648_RS01925 (QA648_01925) 394273..394968 + 696 WP_104822120.1 ATP phosphoribosyltransferase -
QA648_RS01930 (QA648_01930) 395049..395492 - 444 WP_104822121.1 DoxX family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-88)

Antitoxin

Relaxosome protein TraY

(7-50)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10689.30 Da        Isoelectric Point: 10.2777

>T276490 WP_104822116.1 NZ_CP121652:c391097-390828 [Rhizobium sp. CB3171]
VVWTIEYARSARKFVEKLDPKTRRRIRDFLEERLPSLHDPRQVGDALQGAKLGNYWRYRVGDYRIICDLQDSRLVVLVVE
IGNRRDIYR

Download         Length: 270 bp

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8820.82 Da        Isoelectric Point: 4.4290

>AT276490 WP_104822117.1 NZ_CP121652:c391308-391081 [Rhizobium sp. CB3171]
MSKQTAIRLPDETYERLQALAERTGRTATYYIRQAIEAHLQDLEDVYLAERAMERIKKGEDEIVSSEEFWRGLDD

Download         Length: 228 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References