Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | rlegTA/AbiEii-AbiEi |
| Location | 75699..77229 | Replicon | plasmid pCB82_1 |
| Accession | NZ_CP121651 | ||
| Organism | Bradyrhizobium sp. CB82 | ||
Toxin (Protein)
| Gene name | rlegT | Uniprot ID | - |
| Locus tag | QA640_RS44120 | Protein ID | WP_283043593.1 |
| Coordinates | 75699..76592 (-) | Length | 298 a.a. |
Antitoxin (Protein)
| Gene name | rlegA | Uniprot ID | - |
| Locus tag | QA640_RS44125 | Protein ID | WP_283043861.1 |
| Coordinates | 76585..77229 (-) | Length | 215 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| QA640_RS44100 (QA640_44100) | 71435..71578 | - | 144 | Protein_70 | sarcosine oxidase subunit beta | - |
| QA640_RS44105 (QA640_44105) | 71575..71934 | - | 360 | WP_283043591.1 | hypothetical protein | - |
| QA640_RS44110 (QA640_44110) | 72498..73409 | + | 912 | WP_283043592.1 | SDR family NAD(P)-dependent oxidoreductase | - |
| QA640_RS44115 (QA640_44115) | 73837..75234 | + | 1398 | WP_283037453.1 | IS1380 family transposase | - |
| QA640_RS44120 (QA640_44120) | 75699..76592 | - | 894 | WP_283043593.1 | nucleotidyl transferase AbiEii/AbiGii toxin family protein | Toxin |
| QA640_RS44125 (QA640_44125) | 76585..77229 | - | 645 | WP_283043861.1 | type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein | Antitoxin |
| QA640_RS44130 (QA640_44130) | 77372..78721 | - | 1350 | WP_283043862.1 | recombinase family protein | - |
| QA640_RS44135 (QA640_44135) | 78725..79078 | - | 354 | Protein_77 | recombinase family protein | - |
| QA640_RS44140 (QA640_44140) | 79653..80147 | + | 495 | WP_283043594.1 | hypothetical protein | - |
| QA640_RS44145 (QA640_44145) | 80287..80478 | + | 192 | WP_283043595.1 | hypothetical protein | - |
| QA640_RS44150 (QA640_44150) | 80557..80874 | + | 318 | WP_283043596.1 | hypothetical protein | - |
| QA640_RS44155 (QA640_44155) | 80948..81928 | + | 981 | WP_283043597.1 | toprim domain-containing protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Non-Mobilizable plasmid | - | katA | 1..900293 | 900293 | |
| - | flank | IS/Tn | - | - | 73837..75234 | 1397 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 298 a.a. Molecular weight: 33644.75 Da Isoelectric Point: 8.4111
>T276489 WP_283043593.1 NZ_CP121651:c76592-75699 [Bradyrhizobium sp. CB82]
MPKKPKPPIKNMGASVRARLLNLSKQRRQPFDLLLNNYVLERLLYRLSQTKHHDRFILKGAILLTKWFEDPLRPTRDLDF
LAIGNDDQEEMVRIFQEVSAVHFNDGVVIDPDSVKVDRIREETEYGGLRITANAMIDNAKIRVVIDIAFGDSVEPGLQEM
DLPVLLDFPAPHLRAYARETVIAEKFQAMVMLGRANSRMKDLYDVWVLSRNFEFKDGKLPRAIAATFARRKTEIPSEIPD
ALTTAFAEDPTKVQQWNSFSVDVAFRPGTLADVVKDLSAFLVPHASAARSLGETRSA
MPKKPKPPIKNMGASVRARLLNLSKQRRQPFDLLLNNYVLERLLYRLSQTKHHDRFILKGAILLTKWFEDPLRPTRDLDF
LAIGNDDQEEMVRIFQEVSAVHFNDGVVIDPDSVKVDRIREETEYGGLRITANAMIDNAKIRVVIDIAFGDSVEPGLQEM
DLPVLLDFPAPHLRAYARETVIAEKFQAMVMLGRANSRMKDLYDVWVLSRNFEFKDGKLPRAIAATFARRKTEIPSEIPD
ALTTAFAEDPTKVQQWNSFSVDVAFRPGTLADVVKDLSAFLVPHASAARSLGETRSA
Download Length: 894 bp
Antitoxin
Download Length: 215 a.a. Molecular weight: 23858.77 Da Isoelectric Point: 10.9064
>AT276489 WP_283043861.1 NZ_CP121651:c77229-76585 [Bradyrhizobium sp. CB82]
MLSASETQQDRAITLLKKRGMLRLSEFREAGITAATVSRMKEKGLILQLSRGLYQLPDASFDTHHALAEAAKLVPRGVIC
LTSALAFHGLTDTIPSRVWMAIGAKDRRPRIEAPPLQFVRFGEKVLTSGITQQKIEGVQVRIYNPAKTVVDLFRYRRSAG
KRYQKSPGLNLALEGLREALRQRKATPAEIARYANEAGIWKVVQPYLEAMTTNA
MLSASETQQDRAITLLKKRGMLRLSEFREAGITAATVSRMKEKGLILQLSRGLYQLPDASFDTHHALAEAAKLVPRGVIC
LTSALAFHGLTDTIPSRVWMAIGAKDRRPRIEAPPLQFVRFGEKVLTSGITQQKIEGVQVRIYNPAKTVVDLFRYRRSAG
KRYQKSPGLNLALEGLREALRQRKATPAEIARYANEAGIWKVVQPYLEAMTTNA
Download Length: 645 bp
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|