Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | pmenTA/darT(toxin) |
| Location | 5480210..5481482 | Replicon | chromosome |
| Accession | NZ_CP121647 | ||
| Organism | Bradyrhizobium sp. CB3481 | ||
Toxin (Protein)
| Gene name | pmenT | Uniprot ID | - |
| Locus tag | QA643_RS26725 | Protein ID | WP_283028747.1 |
| Coordinates | 5480976..5481482 (-) | Length | 169 a.a. |
Antitoxin (Protein)
| Gene name | pmenA | Uniprot ID | - |
| Locus tag | QA643_RS26715 | Protein ID | WP_283028746.1 |
| Coordinates | 5480210..5480842 (-) | Length | 211 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| QA643_RS26695 (QA643_26695) | 5476622..5476839 | - | 218 | Protein_5269 | SOS response-associated peptidase | - |
| QA643_RS26700 (QA643_26700) | 5476968..5478003 | + | 1036 | Protein_5270 | IS110 family transposase | - |
| QA643_RS26705 (QA643_26705) | 5478726..5479208 | - | 483 | WP_283028743.1 | hypothetical protein | - |
| QA643_RS26710 (QA643_26710) | 5479829..5479830 | - | 2 | WP_283028744.1 | IS630 family transposase | - |
| QA643_RS26715 (QA643_26715) | 5480210..5480842 | - | 633 | WP_283028746.1 | macro domain-containing protein | Antitoxin |
| QA643_RS26720 (QA643_26720) | 5480846..5480953 | - | 108 | WP_283034940.1 | hypothetical protein | - |
| QA643_RS26725 (QA643_26725) | 5480976..5481482 | - | 507 | WP_283028747.1 | DUF4433 domain-containing protein | Toxin |
| QA643_RS26730 (QA643_26730) | 5483339..5485009 | + | 1671 | WP_283028748.1 | nodulation protein NodU | - |
| QA643_RS26735 (QA643_26735) | 5485050..5485208 | + | 159 | WP_283028749.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Genomic island | - | - | 5464820..5485009 | 20189 | |
| - | flank | IS/Tn | - | - | 5479236..5479631 | 395 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 169 a.a. Molecular weight: 19179.08 Da Isoelectric Point: 7.2621
>T276485 WP_283028747.1 NZ_CP121647:c5481482-5480976 [Bradyrhizobium sp. CB3481]
MSKELLNPQKAFIFRICHKSNVEKVLSDGGCMCANDANNSKYVEIGNQELISKRKAHPVPCGPGGTLGDYVPFYFTPFSP
MLYNIKTGYNGIPKRPIEDMVILVTSLHYLEEKSVPFVFTDRHAYLKLAQFSNDLSDLSWIIWSVLQEKNFKKDDMDKFE
KYQAEALA
MSKELLNPQKAFIFRICHKSNVEKVLSDGGCMCANDANNSKYVEIGNQELISKRKAHPVPCGPGGTLGDYVPFYFTPFSP
MLYNIKTGYNGIPKRPIEDMVILVTSLHYLEEKSVPFVFTDRHAYLKLAQFSNDLSDLSWIIWSVLQEKNFKKDDMDKFE
KYQAEALA
Download Length: 507 bp
Antitoxin
Download Length: 211 a.a. Molecular weight: 23692.66 Da Isoelectric Point: 9.3294
>AT276485 WP_283028746.1 NZ_CP121647:c5480842-5480210 [Bradyrhizobium sp. CB3481]
MIRFTQDAEALVNTVNTVGVMGKGVALMFKEAYPENFDAYEAACRSDEVQIGKMFVTERREMFGPKWIVNFPTKAHWRFP
SRIEWIVQGLEDLKRVIKETGIKSVALPPLGAGNGGLAWKDVRPKIEAALGELNDVDVIVYEPTAKYQNVAKRTVMEKLT
ATRALIAELVRRYSILGFDCTLLEIQKLAYFLKRDGVSLNRFGIPKSVCF
MIRFTQDAEALVNTVNTVGVMGKGVALMFKEAYPENFDAYEAACRSDEVQIGKMFVTERREMFGPKWIVNFPTKAHWRFP
SRIEWIVQGLEDLKRVIKETGIKSVALPPLGAGNGGLAWKDVRPKIEAALGELNDVDVIVYEPTAKYQNVAKRTVMEKLT
ATRALIAELVRRYSILGFDCTLLEIQKLAYFLKRDGVSLNRFGIPKSVCF
Download Length: 633 bp
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|