Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-Phd
Location 2465981..2466684 Replicon chromosome
Accession NZ_CP121644
Organism Bradyrhizobium barranii strain CC1502

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag QA633_RS11270 Protein ID WP_063985190.1
Coordinates 2465981..2466406 (-) Length 142 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID A0A8T5VAC8
Locus tag QA633_RS11275 Protein ID WP_028148610.1
Coordinates 2466403..2466684 (-) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QA633_RS11240 (QA633_11240) 2461913..2462323 + 411 WP_063985193.1 acyl-CoA thioesterase -
QA633_RS11245 (QA633_11245) 2462544..2462735 + 192 WP_028134810.1 hypothetical protein -
QA633_RS11250 (QA633_11250) 2463001..2463396 - 396 WP_155795382.1 nuclear transport factor 2 family protein -
QA633_RS11255 (QA633_11255) 2463716..2464183 - 468 WP_231144343.1 nuclear transport factor 2 family protein -
QA633_RS11260 (QA633_11260) 2464338..2465036 + 699 WP_063985192.1 HAD-IA family hydrolase -
QA633_RS11265 (QA633_11265) 2465128..2465976 + 849 WP_063985191.1 DeoR/GlpR family DNA-binding transcription regulator -
QA633_RS11270 (QA633_11270) 2465981..2466406 - 426 WP_063985190.1 type II toxin-antitoxin system VapC family toxin Toxin
QA633_RS11275 (QA633_11275) 2466403..2466684 - 282 WP_028148610.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
QA633_RS11280 (QA633_11280) 2466914..2468464 + 1551 WP_063985189.1 glycerol-3-phosphate dehydrogenase -
QA633_RS11285 (QA633_11285) 2468461..2469537 + 1077 WP_063985188.1 ABC transporter ATP-binding protein -
QA633_RS11290 (QA633_11290) 2469552..2470637 + 1086 WP_063985187.1 ABC transporter ATP-binding protein -
QA633_RS11295 (QA633_11295) 2470637..2471611 + 975 WP_063985186.1 sugar ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-123)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(14-77)


Sequences

Toxin        


Download         Length: 142 a.a.        Molecular weight: 15471.74 Da        Isoelectric Point: 5.1538

>T276481 WP_063985190.1 NZ_CP121644:c2466406-2465981 [Bradyrhizobium barranii]
VNLLLDTNVLSEVQRPAPSPKVLAWLDTVDEDRTFISVASIAELRRGIALLDDGRRRAALVAWLAHDLPARFAQRILPID
HAVAERWGDLMAQSRRNGVALSVMDGFFAATALANDLTLVTRNVKDFAAFGVPLLDPWSDA

Download         Length: 426 bp

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10250.47 Da        Isoelectric Point: 5.1409

>AT276481 WP_028148610.1 NZ_CP121644:c2466684-2466403 [Bradyrhizobium barranii]
MTDRSTAPDSPPTDTWTLANAKARLSEVVDRAQTGPQIITRHGRPNAVVVSADEWARKTARKGTLAEFLLASPLRGADLE
LERVQDEPRDEMP

Download         Length: 282 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References