Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 2359524..2360206 Replicon plasmid pCC1099_1
Accession NZ_CP121642
Organism Rhizobium sp. CC1099

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag QA644_RS32630 Protein ID WP_283073142.1
Coordinates 2359524..2359955 (-) Length 144 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID A0A559TH78
Locus tag QA644_RS32635 Protein ID WP_028739329.1
Coordinates 2359952..2360206 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QA644_RS32610 (QA644_32610) 2355365..2356381 - 1017 WP_283073140.1 TRAP transporter substrate-binding protein -
QA644_RS32615 (QA644_32615) 2356459..2357739 - 1281 WP_239602616.1 TRAP transporter large permease subunit -
QA644_RS32620 (QA644_32620) 2357750..2358310 - 561 WP_283073141.1 TRAP transporter small permease -
QA644_RS32625 (QA644_32625) 2358598..2359251 + 654 WP_092588739.1 TetR family transcriptional regulator -
QA644_RS32630 (QA644_32630) 2359524..2359955 - 432 WP_283073142.1 type II toxin-antitoxin system VapC family toxin Toxin
QA644_RS32635 (QA644_32635) 2359952..2360206 - 255 WP_028739329.1 plasmid stabilization protein Antitoxin
QA644_RS32640 (QA644_32640) 2360576..2360881 - 306 Protein_2286 transcriptional regulator -
QA644_RS32645 (QA644_32645) 2360984..2361810 - 827 Protein_2287 carbohydrate ABC transporter permease -
QA644_RS32650 (QA644_32650) 2361814..2362647 - 834 WP_283074074.1 sugar ABC transporter permease -
QA644_RS32655 (QA644_32655) 2362750..2364018 - 1269 Protein_2289 ABC transporter substrate-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - katA / htpB 1..2523472 2523472


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-126)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 144 a.a.        Molecular weight: 15572.10 Da        Isoelectric Point: 7.0148

>T276479 WP_283073142.1 NZ_CP121642:c2359955-2359524 [Rhizobium sp. CC1099]
MILLDTNVISEPWKPVPDGAVIEWMDAQAIETLFLSAITIAELRFGIAAMPSGKRQIILRDRLEGEVLPHFAERILPFGL
ATSQFYSELMVRARVSGKAIGKADGYIAATAAANGLAVATRDTSPFEAAGVKVINPWSLQKRY

Download         Length: 432 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9307.45 Da        Isoelectric Point: 6.4840

>AT276479 WP_028739329.1 NZ_CP121642:c2360206-2359952 [Rhizobium sp. CC1099]
MPAVTIRNLSDETHRALRVRAAHHGRSTEAEIRDIIEAAVRPSERVKLGSLLAAIGRDAELSNHDVEALQQNRDKAPAEP
MTFE

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A559TH78

References