Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /RES-Xre
Location 1370537..1371407 Replicon plasmid pCC1099_1
Accession NZ_CP121642
Organism Rhizobium sp. CC1099

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag QA644_RS27705 Protein ID WP_283072534.1
Coordinates 1370537..1371043 (-) Length 169 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID A0A1L5NV54
Locus tag QA644_RS27710 Protein ID WP_074072035.1
Coordinates 1371036..1371407 (-) Length 124 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QA644_RS27690 (QA644_27690) 1366992..1368404 + 1413 WP_283072532.1 FAD/NAD(P)-binding protein -
QA644_RS27695 (QA644_27695) 1368714..1370210 + 1497 WP_283074037.1 DegQ family serine endoprotease -
QA644_RS27700 (QA644_27700) 1370253..1370510 - 258 WP_283072533.1 hypothetical protein -
QA644_RS27705 (QA644_27705) 1370537..1371043 - 507 WP_283072534.1 RES domain-containing protein Toxin
QA644_RS27710 (QA644_27710) 1371036..1371407 - 372 WP_074072035.1 DUF2384 domain-containing protein Antitoxin
QA644_RS27715 (QA644_27715) 1371470..1372261 - 792 WP_239600559.1 crotonase/enoyl-CoA hydratase family protein -
QA644_RS27720 (QA644_27720) 1372258..1373127 - 870 WP_194731926.1 hydroxymethylglutaryl-CoA lyase -
QA644_RS27725 (QA644_27725) 1373127..1375106 - 1980 WP_283072535.1 acetyl/propionyl/methylcrotonyl-CoA carboxylase subunit alpha -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - katA / htpB 1..2523472 2523472


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(7-161)

Antitoxin

Antitoxin Xre/MbcA/ParS-like, toxin-binding domain

(71-120)


Sequences

Toxin        


Download         Length: 169 a.a.        Molecular weight: 19006.87 Da        Isoelectric Point: 7.8437

>T276476 WP_283072534.1 NZ_CP121642:c1371043-1370537 [Rhizobium sp. CC1099]
MPETVVHLWRAFVPRWAHAPLSGEGASRFGGRWNRVGAPTIYAACELSTAWAEYNQGFVQHPAMIVQLELKGARLADTTD
QMLLRKFDVTADIYRCEWRMLMDESKVPATHHLRERLIASRYHGAIYPSFMSLGGTCVALWEWNMPGAPELRAIDPDGRL
PKSPASWL

Download         Length: 507 bp

Antitoxin


Download         Length: 124 a.a.        Molecular weight: 13057.91 Da        Isoelectric Point: 10.1453

>AT276476 WP_074072035.1 NZ_CP121642:c1371407-1371036 [Rhizobium sp. CC1099]
MAATGLSNVAARFGDEHSSFLSARRVAEQLGVTLSELARLIGVARNTLAAKSGARKVDNALSNVVRILAMASEMAGDENR
AVIWFKHQPIPGWGGKTAFDLVGEGKSDRVLAYLEAVRSGVYA

Download         Length: 372 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A1L5NV54

References