Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | PP_4151-4152/excise(antitoxin) |
| Location | 4012174..4012960 | Replicon | chromosome |
| Accession | NZ_CP121641 | ||
| Organism | Rhizobium sp. CC1099 | ||
Toxin (Protein)
| Gene name | PP_4152 | Uniprot ID | - |
| Locus tag | QA644_RS19865 | Protein ID | WP_283070202.1 |
| Coordinates | 4012688..4012960 (+) | Length | 91 a.a. |
Antitoxin (Protein)
| Gene name | PP_4151 | Uniprot ID | - |
| Locus tag | QA644_RS19860 | Protein ID | WP_183906422.1 |
| Coordinates | 4012174..4012620 (+) | Length | 149 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| QA644_RS19835 (QA644_19835) | 4008302..4010002 | - | 1701 | WP_022713201.1 | 30S ribosomal protein S1 | - |
| QA644_RS19840 (QA644_19840) | 4010179..4010823 | - | 645 | WP_074066193.1 | (d)CMP kinase | - |
| QA644_RS19845 (QA644_19845) | 4010820..4011107 | - | 288 | WP_283070195.1 | hypothetical protein | - |
| QA644_RS19850 (QA644_19850) | 4011325..4011708 | + | 384 | WP_022713204.1 | TIGR02300 family protein | - |
| QA644_RS19860 (QA644_19860) | 4012174..4012620 | + | 447 | WP_183906422.1 | helix-turn-helix domain-containing protein | Antitoxin |
| QA644_RS19865 (QA644_19865) | 4012688..4012960 | + | 273 | WP_283070202.1 | hypothetical protein | Toxin |
| QA644_RS19870 (QA644_19870) | 4013471..4014595 | + | 1125 | WP_283070204.1 | DNA replication/repair protein RecF | - |
| QA644_RS19875 (QA644_19875) | 4014592..4015416 | + | 825 | WP_239596210.1 | molybdopterin-synthase adenylyltransferase MoeB | - |
| QA644_RS19880 (QA644_19880) | 4015413..4015886 | + | 474 | WP_283070207.1 | GNAT family N-acetyltransferase | - |
| QA644_RS19885 (QA644_19885) | 4015883..4016884 | - | 1002 | WP_074066199.1 | D-glycerate dehydrogenase | - |
| QA644_RS19890 (QA644_19890) | 4017071..4017610 | + | 540 | WP_283070210.1 | SH3 domain-containing protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 91 a.a. Molecular weight: 10118.26 Da Isoelectric Point: 4.3603
>T276475 WP_283070202.1 NZ_CP121641:4012688-4012960 [Rhizobium sp. CC1099]
MELAAAGQFRAKWSDEIHDEWTRNVLKNRDDLTIEQLGRTKDLMNAAVPDSVVDGYSDLVPALALPDPDDSRASGVTQDR
SRLREYLFAI
MELAAAGQFRAKWSDEIHDEWTRNVLKNRDDLTIEQLGRTKDLMNAAVPDSVVDGYSDLVPALALPDPDDSRASGVTQDR
SRLREYLFAI
Download Length: 273 bp
Antitoxin
Download Length: 149 a.a. Molecular weight: 16618.01 Da Isoelectric Point: 5.9324
>AT276475 WP_183906422.1 NZ_CP121641:4012174-4012620 [Rhizobium sp. CC1099]
MSQLLERPILPSADDTELAAEASRYISRAKHEGAELRVQVDGGELLKLPKAVSELLYHLLTEMAQGNAVTLIPVHAELTT
QEAADHLNVSRPYLIKLLEEGKIPFHMVGSHRRIKFSDLDGFRRKAEDERKRLMDELASQAQDLGMGY
MSQLLERPILPSADDTELAAEASRYISRAKHEGAELRVQVDGGELLKLPKAVSELLYHLLTEMAQGNAVTLIPVHAELTT
QEAADHLNVSRPYLIKLLEEGKIPFHMVGSHRRIKFSDLDGFRRKAEDERKRLMDELASQAQDLGMGY
Download Length: 447 bp
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|