Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/LOTUS_5_Limkain_b1(toxin)
Location 703256..703830 Replicon chromosome
Accession NZ_CP121641
Organism Rhizobium sp. CC1099

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag QA644_RS03450 Protein ID WP_283071085.1
Coordinates 703465..703830 (+) Length 122 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag QA644_RS03445 Protein ID WP_194729179.1
Coordinates 703256..703471 (+) Length 72 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QA644_RS03420 (QA644_03420) 699469..700422 - 954 WP_022716380.1 sulfate adenylyltransferase subunit CysD -
QA644_RS03425 (QA644_03425) 700580..701320 - 741 WP_074066964.1 phosphoadenylyl-sulfate reductase -
QA644_RS03430 (QA644_03430) 701744..702190 + 447 WP_022716377.1 Rrf2 family transcriptional regulator -
QA644_RS03435 (QA644_03435) 702330..702716 + 387 WP_028739821.1 DUF6152 family protein -
QA644_RS03440 (QA644_03440) 702721..703197 + 477 WP_074066966.1 DUF2214 domain-containing protein -
QA644_RS03445 (QA644_03445) 703256..703471 + 216 WP_194729179.1 CopG family transcriptional regulator Antitoxin
QA644_RS03450 (QA644_03450) 703465..703830 + 366 WP_283071085.1 type II toxin-antitoxin system VapC family toxin Toxin
QA644_RS03455 (QA644_03455) 703890..704033 + 144 WP_283071086.1 type II toxin-antitoxin system RelE/ParE family toxin -
QA644_RS03460 (QA644_03460) 704252..705901 - 1650 WP_239595110.1 choline dehydrogenase -
QA644_RS03465 (QA644_03465) 705962..707425 - 1464 WP_283071087.1 betaine-aldehyde dehydrogenase -
QA644_RS03470 (QA644_03470) 707490..708074 - 585 WP_283071088.1 transcriptional regulator BetI -
QA644_RS03475 (QA644_03475) 708217..708771 + 555 WP_283071089.1 HdeD family acid-resistance protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-106)

Antitoxin

Ribbon-helix-helix protein, CopG

(9-40)


Sequences

Toxin        


Download         Length: 122 a.a.        Molecular weight: 13637.63 Da        Isoelectric Point: 6.2250

>T276474 WP_283071085.1 NZ_CP121641:703465-703830 [Rhizobium sp. CC1099]
MVKALFDTNILIDYLNAIPEARDELDRYGRRAISVVTWMEVLIGADPDVEAATRSFLNNFQIIAVDNVIAEGAVRLRQHH
RIKLPDAIIWSTADAHASLLVTRNTKDFPADNPGIRVPYLR

Download         Length: 366 bp

Antitoxin


Download         Length: 72 a.a.        Molecular weight: 8306.51 Da        Isoelectric Point: 8.6003

>AT276474 WP_194729179.1 NZ_CP121641:703256-703471 [Rhizobium sp. CC1099]
MRILVDIVESELKALDKMAKSEKVSRASLIRKAVNDFLDRHDRTKEAEAFGLWGNRKIDGLEYQDKVRSEW

Download         Length: 216 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References