Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-Phd
Location 7397565..7398265 Replicon chromosome
Accession NZ_CP121634
Organism Bradyrhizobium sp. CIAT3101

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag QA645_RS34540 Protein ID WP_283045689.1
Coordinates 7397840..7398265 (+) Length 142 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag QA645_RS34535 Protein ID WP_283045688.1
Coordinates 7397565..7397843 (+) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QA645_RS34515 (QA645_34515) 7392710..7393612 - 903 WP_283045685.1 sugar ABC transporter permease -
QA645_RS34520 (QA645_34520) 7393612..7394697 - 1086 WP_283045686.1 ABC transporter ATP-binding protein -
QA645_RS34525 (QA645_34525) 7394710..7395786 - 1077 WP_254129261.1 ABC transporter ATP-binding protein -
QA645_RS34530 (QA645_34530) 7395783..7397333 - 1551 WP_283045687.1 glycerol-3-phosphate dehydrogenase -
QA645_RS34535 (QA645_34535) 7397565..7397843 + 279 WP_283045688.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
QA645_RS34540 (QA645_34540) 7397840..7398265 + 426 WP_283045689.1 type II toxin-antitoxin system VapC family toxin Toxin
QA645_RS34545 (QA645_34545) 7398270..7399118 - 849 WP_254129257.1 DeoR/GlpR family DNA-binding transcription regulator -
QA645_RS34550 (QA645_34550) 7399193..7399882 - 690 WP_283045690.1 HAD-IA family hydrolase -
QA645_RS34555 (QA645_34555) 7400037..7400504 + 468 WP_283045691.1 nuclear transport factor 2 family protein -
QA645_RS34560 (QA645_34560) 7400560..7400970 + 411 WP_254196171.1 nuclear transport factor 2 family protein -
QA645_RS34565 (QA645_34565) 7401125..7401316 - 192 WP_237866489.1 hypothetical protein -
QA645_RS34570 (QA645_34570) 7401539..7401949 - 411 WP_283045692.1 acyl-CoA thioesterase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-123)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(13-77)


Sequences

Toxin        


Download         Length: 142 a.a.        Molecular weight: 15546.91 Da        Isoelectric Point: 6.4708

>T276467 WP_283045689.1 NZ_CP121634:7397840-7398265 [Bradyrhizobium sp. CIAT3101]
VNLLLDTNVLSEVQRPVPSPKVLAWLDTVDEDRAFISVASIAELRRGVALLDDGRRRVALTAWLSHDLPARFAERILPID
HTVAERWGDLMAQSRRSGIALSVMDGFFAATALAQNLTLVTRNMKNFAAFGVPLLNPWDAA

Download         Length: 426 bp

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10221.58 Da        Isoelectric Point: 7.2062

>AT276467 WP_283045688.1 NZ_CP121634:7397565-7397843 [Bradyrhizobium sp. CIAT3101]
MTEHTTAPKSPTDTWTLANAKARLSEVVDRAQTGPQIITRHGKPNAVVVSADEWARKTARKGTLAEFLLASPLRGAELEL
ERMRDEPRDEMP

Download         Length: 279 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References