Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 3182420..3183073 Replicon chromosome
Accession NZ_CP121632
Organism Acinetobacter baumannii strain HAB11

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag MTT06_RS15445 Protein ID WP_000607077.1
Coordinates 3182684..3183073 (+) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID V5V966
Locus tag MTT06_RS15440 Protein ID WP_001288210.1
Coordinates 3182420..3182677 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MTT06_RS15420 (MTT06_15420) 3177936..3178943 + 1008 WP_000198631.1 DNA-directed RNA polymerase subunit alpha -
MTT06_RS15425 (MTT06_15425) 3178962..3179339 + 378 WP_001216380.1 50S ribosomal protein L17 -
MTT06_RS15430 (MTT06_15430) 3179521..3181011 + 1491 WP_000415125.1 NAD(P)/FAD-dependent oxidoreductase -
MTT06_RS15435 (MTT06_15435) 3181060..3182232 - 1173 WP_001190542.1 acyl-CoA dehydrogenase family protein -
MTT06_RS15440 (MTT06_15440) 3182420..3182677 + 258 WP_001288210.1 succinate dehydrogenase assembly factor 2 Antitoxin
MTT06_RS15445 (MTT06_15445) 3182684..3183073 + 390 WP_000607077.1 membrane protein Toxin
MTT06_RS15450 (MTT06_15450) 3183843..3184928 + 1086 WP_000049106.1 hypothetical protein -
MTT06_RS15455 (MTT06_15455) 3185006..3185572 + 567 WP_000651538.1 rhombosortase -
MTT06_RS15460 (MTT06_15460) 3185760..3187955 + 2196 WP_001158906.1 TRAP transporter large permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(10-82)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15552.88 Da        Isoelectric Point: 10.4313

>T276463 WP_000607077.1 NZ_CP121632:3182684-3183073 [Acinetobacter baumannii]
MINHLNFKLKYSRFSIIFQFFIGLSLAVLFYQLMPLLWWLVVISLLFISFIFFLKRPQLAQIAYLDKKLWSLAYKSQNTV
SRVKILKIIDCQIFIVIYFEGHKTLTSIIWFDQMSLAEWKKLKTLEKLY

Download         Length: 390 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10318.77 Da        Isoelectric Point: 4.6150

>AT276463 WP_001288210.1 NZ_CP121632:3182420-3182677 [Acinetobacter baumannii]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A7U4BQM7

References