Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 3241756..3242409 Replicon chromosome
Accession NZ_CP121625
Organism Acinetobacter baumannii strain JAB144

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag MTS17_RS15830 Protein ID WP_000607077.1
Coordinates 3242020..3242409 (+) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID V5V966
Locus tag MTS17_RS15825 Protein ID WP_001288210.1
Coordinates 3241756..3242013 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MTS17_RS15805 (MTS17_15805) 3237272..3238279 + 1008 WP_000198631.1 DNA-directed RNA polymerase subunit alpha -
MTS17_RS15810 (MTS17_15810) 3238298..3238675 + 378 WP_001216380.1 50S ribosomal protein L17 -
MTS17_RS15815 (MTS17_15815) 3238857..3240347 + 1491 WP_000415125.1 NAD(P)/FAD-dependent oxidoreductase -
MTS17_RS15820 (MTS17_15820) 3240396..3241568 - 1173 WP_001190542.1 acyl-CoA dehydrogenase family protein -
MTS17_RS15825 (MTS17_15825) 3241756..3242013 + 258 WP_001288210.1 succinate dehydrogenase assembly factor 2 Antitoxin
MTS17_RS15830 (MTS17_15830) 3242020..3242409 + 390 WP_000607077.1 membrane protein Toxin
MTS17_RS15835 (MTS17_15835) 3243179..3244264 + 1086 WP_000049106.1 hypothetical protein -
MTS17_RS15840 (MTS17_15840) 3244342..3244908 + 567 WP_000651538.1 rhombosortase -
MTS17_RS15845 (MTS17_15845) 3245096..3247291 + 2196 WP_001158906.1 TRAP transporter large permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(10-82)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15552.88 Da        Isoelectric Point: 10.4313

>T276456 WP_000607077.1 NZ_CP121625:3242020-3242409 [Acinetobacter baumannii]
MINHLNFKLKYSRFSIIFQFFIGLSLAVLFYQLMPLLWWLVVISLLFISFIFFLKRPQLAQIAYLDKKLWSLAYKSQNTV
SRVKILKIIDCQIFIVIYFEGHKTLTSIIWFDQMSLAEWKKLKTLEKLY

Download         Length: 390 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10318.77 Da        Isoelectric Point: 4.6150

>AT276456 WP_001288210.1 NZ_CP121625:3241756-3242013 [Acinetobacter baumannii]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A7U4BQM7

References