276453

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) BrnTA/BrnT-BrnA
Location 787..1402 Replicon plasmid pII_JAB117
Accession NZ_CP121613
Organism Acinetobacter baumannii strain JAB117

Toxin (Protein)


Gene name brnT Uniprot ID A0A3G6Z3M6
Locus tag MTS71_RS19270 Protein ID WP_000438826.1
Coordinates 1115..1402 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name brnA Uniprot ID -
Locus tag MTS71_RS19265 Protein ID WP_200165042.1
Coordinates 787..1128 (-) Length 114 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MTS71_RS19265 (MTS71_19265) 787..1128 - 342 WP_200165042.1 BrnA antitoxin family protein Antitoxin
MTS71_RS19270 (MTS71_19270) 1115..1402 - 288 WP_000438826.1 BrnT family toxin Toxin
MTS71_RS19275 (MTS71_19275) 1774..2291 + 518 Protein_3 tetratricopeptide repeat protein -
MTS71_RS19280 (MTS71_19280) 2442..2621 - 180 WP_151277549.1 hypothetical protein -
MTS71_RS19285 (MTS71_19285) 2641..3214 - 574 Protein_5 plasmid replication DNA-binding protein -
MTS71_RS19290 (MTS71_19290) 3215..4156 - 942 WP_060853654.1 replication initiation protein RepM -
MTS71_RS19295 (MTS71_19295) 5366..5737 + 372 WP_000504218.1 hypothetical protein -
MTS71_RS19300 (MTS71_19300) 5737..5910 + 174 WP_001282484.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..17446 17446


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(7-88)

Antitoxin

BrnA antitoxin of type II toxin-antitoxin system

(41-96)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11303.72 Da        Isoelectric Point: 6.0889

>T276453 WP_000438826.1 NZ_CP121613:c1402-1115 [Acinetobacter baumannii]
MEQYFEWDEAKNRKNQKKHDISFETASLVFEDPLRISIQDRHTNGEERWQTIGRVKGVLMLLVAHTIFDEDDCEIIRIIS
ARQVTKAERNKYEHG

Download         Length: 288 bp

Antitoxin


Download         Length: 114 a.a.        Molecular weight: 13097.90 Da        Isoelectric Point: 8.4751

>AT276453 WP_200165042.1 NZ_CP121613:c1128-787 [Acinetobacter baumannii]
MSMVRYSHKELNEKFGEKQDAEIQRLLAKGTVPDDQLDLSDIPEITDWSNAVRQNQFYRPVKQQTSIRLDADVLAWFKAQ
GKGYQTRMNEILRDAMLKELKIINKNGSLGSHF

Download         Length: 342 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3G6Z3M6

Antitoxin

Source ID Structure

References