Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 3265012..3265665 Replicon chromosome
Accession NZ_CP121595
Organism Acinetobacter baumannii strain MAB17

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag MTS72_RS15600 Protein ID WP_000607077.1
Coordinates 3265012..3265401 (-) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID V5V966
Locus tag MTS72_RS15605 Protein ID WP_001288210.1
Coordinates 3265408..3265665 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MTS72_RS15585 (MTS72_15585) 3260130..3262325 - 2196 WP_001158906.1 TRAP transporter large permease subunit -
MTS72_RS15590 (MTS72_15590) 3262513..3263079 - 567 WP_000651538.1 rhombosortase -
MTS72_RS15595 (MTS72_15595) 3263157..3264242 - 1086 WP_000049106.1 hypothetical protein -
MTS72_RS15600 (MTS72_15600) 3265012..3265401 - 390 WP_000607077.1 membrane protein Toxin
MTS72_RS15605 (MTS72_15605) 3265408..3265665 - 258 WP_001288210.1 succinate dehydrogenase assembly factor 2 Antitoxin
MTS72_RS15610 (MTS72_15610) 3265853..3267025 + 1173 WP_001190542.1 acyl-CoA dehydrogenase family protein -
MTS72_RS15615 (MTS72_15615) 3267074..3268564 - 1491 WP_000415125.1 NAD(P)/FAD-dependent oxidoreductase -
MTS72_RS15620 (MTS72_15620) 3268746..3269123 - 378 WP_001216380.1 50S ribosomal protein L17 -
MTS72_RS15625 (MTS72_15625) 3269142..3270149 - 1008 WP_000198631.1 DNA-directed RNA polymerase subunit alpha -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(10-82)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15552.88 Da        Isoelectric Point: 10.4313

>T276441 WP_000607077.1 NZ_CP121595:c3265401-3265012 [Acinetobacter baumannii]
MINHLNFKLKYSRFSIIFQFFIGLSLAVLFYQLMPLLWWLVVISLLFISFIFFLKRPQLAQIAYLDKKLWSLAYKSQNTV
SRVKILKIIDCQIFIVIYFEGHKTLTSIIWFDQMSLAEWKKLKTLEKLY

Download         Length: 390 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10318.77 Da        Isoelectric Point: 4.6150

>AT276441 WP_001288210.1 NZ_CP121595:c3265665-3265408 [Acinetobacter baumannii]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A7U4BQM7

References