Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 430201..430854 Replicon chromosome
Accession NZ_CP121588
Organism Acinetobacter baumannii strain MAB9

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag MTS46_RS02110 Protein ID WP_000607077.1
Coordinates 430465..430854 (+) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID V5V966
Locus tag MTS46_RS02105 Protein ID WP_001288210.1
Coordinates 430201..430458 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MTS46_RS02085 (MTS46_02085) 425717..426724 + 1008 WP_000198631.1 DNA-directed RNA polymerase subunit alpha -
MTS46_RS02090 (MTS46_02090) 426743..427120 + 378 WP_064894046.1 50S ribosomal protein L17 -
MTS46_RS02095 (MTS46_02095) 427302..428792 + 1491 WP_000415125.1 NAD(P)/FAD-dependent oxidoreductase -
MTS46_RS02100 (MTS46_02100) 428841..430013 - 1173 WP_001190542.1 acyl-CoA dehydrogenase family protein -
MTS46_RS02105 (MTS46_02105) 430201..430458 + 258 WP_001288210.1 succinate dehydrogenase assembly factor 2 Antitoxin
MTS46_RS02110 (MTS46_02110) 430465..430854 + 390 WP_000607077.1 membrane protein Toxin
MTS46_RS02115 (MTS46_02115) 431624..432709 + 1086 WP_000049106.1 hypothetical protein -
MTS46_RS02120 (MTS46_02120) 432787..433353 + 567 WP_000651538.1 rhombosortase -
MTS46_RS02125 (MTS46_02125) 433541..435736 + 2196 WP_001158906.1 TRAP transporter large permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(10-82)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15552.88 Da        Isoelectric Point: 10.4313

>T276437 WP_000607077.1 NZ_CP121588:430465-430854 [Acinetobacter baumannii]
MINHLNFKLKYSRFSIIFQFFIGLSLAVLFYQLMPLLWWLVVISLLFISFIFFLKRPQLAQIAYLDKKLWSLAYKSQNTV
SRVKILKIIDCQIFIVIYFEGHKTLTSIIWFDQMSLAEWKKLKTLEKLY

Download         Length: 390 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10318.77 Da        Isoelectric Point: 4.6150

>AT276437 WP_001288210.1 NZ_CP121588:430201-430458 [Acinetobacter baumannii]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A7U4BQM7

References