Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 1144439..1145092 Replicon chromosome
Accession NZ_CP121586
Organism Acinetobacter baumannii strain RAB11

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag MTS20_RS05530 Protein ID WP_000607077.1
Coordinates 1144703..1145092 (+) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID V5V966
Locus tag MTS20_RS05525 Protein ID WP_001288210.1
Coordinates 1144439..1144696 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MTS20_RS05505 (MTS20_05505) 1139955..1140962 + 1008 WP_000198631.1 DNA-directed RNA polymerase subunit alpha -
MTS20_RS05510 (MTS20_05510) 1140981..1141358 + 378 WP_001216380.1 50S ribosomal protein L17 -
MTS20_RS05515 (MTS20_05515) 1141540..1143030 + 1491 WP_000415125.1 NAD(P)/FAD-dependent oxidoreductase -
MTS20_RS05520 (MTS20_05520) 1143079..1144251 - 1173 WP_001190542.1 acyl-CoA dehydrogenase family protein -
MTS20_RS05525 (MTS20_05525) 1144439..1144696 + 258 WP_001288210.1 succinate dehydrogenase assembly factor 2 Antitoxin
MTS20_RS05530 (MTS20_05530) 1144703..1145092 + 390 WP_000607077.1 membrane protein Toxin
MTS20_RS05535 (MTS20_05535) 1145862..1146947 + 1086 WP_000049106.1 hypothetical protein -
MTS20_RS05540 (MTS20_05540) 1147025..1147591 + 567 WP_000651538.1 rhombosortase -
MTS20_RS05545 (MTS20_05545) 1147779..1149974 + 2196 WP_001158906.1 TRAP transporter large permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(10-82)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15552.88 Da        Isoelectric Point: 10.4313

>T276434 WP_000607077.1 NZ_CP121586:1144703-1145092 [Acinetobacter baumannii]
MINHLNFKLKYSRFSIIFQFFIGLSLAVLFYQLMPLLWWLVVISLLFISFIFFLKRPQLAQIAYLDKKLWSLAYKSQNTV
SRVKILKIIDCQIFIVIYFEGHKTLTSIIWFDQMSLAEWKKLKTLEKLY

Download         Length: 390 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10318.77 Da        Isoelectric Point: 4.6150

>AT276434 WP_001288210.1 NZ_CP121586:1144439-1144696 [Acinetobacter baumannii]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A7U4BQM7

References