276431

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 3911450..3912103 Replicon chromosome
Accession NZ_CP121583
Organism Acinetobacter baumannii strain RAB14

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag MTS22_RS18730 Protein ID WP_000607077.1
Coordinates 3911714..3912103 (+) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID V5V966
Locus tag MTS22_RS18725 Protein ID WP_001288210.1
Coordinates 3911450..3911707 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MTS22_RS18705 (MTS22_18705) 3906966..3907973 + 1008 WP_000198631.1 DNA-directed RNA polymerase subunit alpha -
MTS22_RS18710 (MTS22_18710) 3907992..3908369 + 378 WP_001216380.1 50S ribosomal protein L17 -
MTS22_RS18715 (MTS22_18715) 3908551..3910041 + 1491 WP_000415125.1 NAD(P)/FAD-dependent oxidoreductase -
MTS22_RS18720 (MTS22_18720) 3910090..3911262 - 1173 WP_001190542.1 acyl-CoA dehydrogenase family protein -
MTS22_RS18725 (MTS22_18725) 3911450..3911707 + 258 WP_001288210.1 succinate dehydrogenase assembly factor 2 Antitoxin
MTS22_RS18730 (MTS22_18730) 3911714..3912103 + 390 WP_000607077.1 membrane protein Toxin
MTS22_RS18735 (MTS22_18735) 3912873..3913958 + 1086 WP_000049106.1 hypothetical protein -
MTS22_RS18740 (MTS22_18740) 3914036..3914602 + 567 WP_000651538.1 rhombosortase -
MTS22_RS18745 (MTS22_18745) 3914790..3916985 + 2196 WP_001158906.1 TRAP transporter large permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(10-82)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15552.88 Da        Isoelectric Point: 10.4313

>T276431 WP_000607077.1 NZ_CP121583:3911714-3912103 [Acinetobacter baumannii]
MINHLNFKLKYSRFSIIFQFFIGLSLAVLFYQLMPLLWWLVVISLLFISFIFFLKRPQLAQIAYLDKKLWSLAYKSQNTV
SRVKILKIIDCQIFIVIYFEGHKTLTSIIWFDQMSLAEWKKLKTLEKLY

Download         Length: 390 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10318.77 Da        Isoelectric Point: 4.6150

>AT276431 WP_001288210.1 NZ_CP121583:3911450-3911707 [Acinetobacter baumannii]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A7U4BQM7

References