Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 3326312..3326965 Replicon chromosome
Accession NZ_CP121579
Organism Acinetobacter baumannii strain RAB53

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag MTS70_RS16005 Protein ID WP_000607077.1
Coordinates 3326312..3326701 (-) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID V5V966
Locus tag MTS70_RS16010 Protein ID WP_001288210.1
Coordinates 3326708..3326965 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MTS70_RS15990 (MTS70_15990) 3321430..3323625 - 2196 WP_001158906.1 TRAP transporter large permease subunit -
MTS70_RS15995 (MTS70_15995) 3323813..3324379 - 567 WP_000651538.1 rhombosortase -
MTS70_RS16000 (MTS70_16000) 3324457..3325542 - 1086 WP_000049106.1 hypothetical protein -
MTS70_RS16005 (MTS70_16005) 3326312..3326701 - 390 WP_000607077.1 membrane protein Toxin
MTS70_RS16010 (MTS70_16010) 3326708..3326965 - 258 WP_001288210.1 succinate dehydrogenase assembly factor 2 Antitoxin
MTS70_RS16015 (MTS70_16015) 3327153..3328325 + 1173 WP_001190542.1 acyl-CoA dehydrogenase family protein -
MTS70_RS16020 (MTS70_16020) 3328374..3329864 - 1491 WP_000415125.1 NAD(P)/FAD-dependent oxidoreductase -
MTS70_RS16025 (MTS70_16025) 3330046..3330423 - 378 WP_001216380.1 50S ribosomal protein L17 -
MTS70_RS16030 (MTS70_16030) 3330442..3331449 - 1008 WP_000198631.1 DNA-directed RNA polymerase subunit alpha -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(10-82)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15552.88 Da        Isoelectric Point: 10.4313

>T276428 WP_000607077.1 NZ_CP121579:c3326701-3326312 [Acinetobacter baumannii]
MINHLNFKLKYSRFSIIFQFFIGLSLAVLFYQLMPLLWWLVVISLLFISFIFFLKRPQLAQIAYLDKKLWSLAYKSQNTV
SRVKILKIIDCQIFIVIYFEGHKTLTSIIWFDQMSLAEWKKLKTLEKLY

Download         Length: 390 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10318.77 Da        Isoelectric Point: 4.6150

>AT276428 WP_001288210.1 NZ_CP121579:c3326965-3326708 [Acinetobacter baumannii]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A7U4BQM7

References