276425

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 74486..75139 Replicon chromosome
Accession NZ_CP121577
Organism Acinetobacter baumannii strain RAB55

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag MTS49_RS00375 Protein ID WP_000607077.1
Coordinates 74486..74875 (-) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID V5V966
Locus tag MTS49_RS00380 Protein ID WP_001288210.1
Coordinates 74882..75139 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MTS49_RS00360 (MTS49_00360) 69604..71799 - 2196 WP_001158906.1 TRAP transporter large permease subunit -
MTS49_RS00365 (MTS49_00365) 71987..72553 - 567 WP_000651538.1 rhombosortase -
MTS49_RS00370 (MTS49_00370) 72631..73716 - 1086 WP_000049106.1 hypothetical protein -
MTS49_RS00375 (MTS49_00375) 74486..74875 - 390 WP_000607077.1 membrane protein Toxin
MTS49_RS00380 (MTS49_00380) 74882..75139 - 258 WP_001288210.1 succinate dehydrogenase assembly factor 2 Antitoxin
MTS49_RS00385 (MTS49_00385) 75327..76499 + 1173 WP_001190542.1 acyl-CoA dehydrogenase family protein -
MTS49_RS00390 (MTS49_00390) 76548..78038 - 1491 WP_000415125.1 NAD(P)/FAD-dependent oxidoreductase -
MTS49_RS00395 (MTS49_00395) 78220..78597 - 378 WP_001216380.1 50S ribosomal protein L17 -
MTS49_RS00400 (MTS49_00400) 78616..79623 - 1008 WP_000198631.1 DNA-directed RNA polymerase subunit alpha -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(10-82)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15552.88 Da        Isoelectric Point: 10.4313

>T276425 WP_000607077.1 NZ_CP121577:c74875-74486 [Acinetobacter baumannii]
MINHLNFKLKYSRFSIIFQFFIGLSLAVLFYQLMPLLWWLVVISLLFISFIFFLKRPQLAQIAYLDKKLWSLAYKSQNTV
SRVKILKIIDCQIFIVIYFEGHKTLTSIIWFDQMSLAEWKKLKTLEKLY

Download         Length: 390 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10318.77 Da        Isoelectric Point: 4.6150

>AT276425 WP_001288210.1 NZ_CP121577:c75139-74882 [Acinetobacter baumannii]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A7U4BQM7

References