Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 79300..79953 Replicon chromosome
Accession NZ_CP121567
Organism Acinetobacter baumannii strain RAB73

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag MTS81_RS00410 Protein ID WP_000607077.1
Coordinates 79300..79689 (-) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID V5V966
Locus tag MTS81_RS00415 Protein ID WP_001288210.1
Coordinates 79696..79953 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MTS81_RS00395 (MTS81_00395) 74418..76613 - 2196 WP_001158906.1 TRAP transporter large permease subunit -
MTS81_RS00400 (MTS81_00400) 76801..77367 - 567 WP_000651538.1 rhombosortase -
MTS81_RS00405 (MTS81_00405) 77445..78530 - 1086 WP_000049106.1 hypothetical protein -
MTS81_RS00410 (MTS81_00410) 79300..79689 - 390 WP_000607077.1 membrane protein Toxin
MTS81_RS00415 (MTS81_00415) 79696..79953 - 258 WP_001288210.1 succinate dehydrogenase assembly factor 2 Antitoxin
MTS81_RS00420 (MTS81_00420) 80141..81313 + 1173 WP_001190542.1 acyl-CoA dehydrogenase family protein -
MTS81_RS00425 (MTS81_00425) 81362..82852 - 1491 WP_000415125.1 NAD(P)/FAD-dependent oxidoreductase -
MTS81_RS00430 (MTS81_00430) 83034..83411 - 378 WP_001216380.1 50S ribosomal protein L17 -
MTS81_RS00435 (MTS81_00435) 83430..84437 - 1008 WP_000198631.1 DNA-directed RNA polymerase subunit alpha -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(10-82)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15552.88 Da        Isoelectric Point: 10.4313

>T276421 WP_000607077.1 NZ_CP121567:c79689-79300 [Acinetobacter baumannii]
MINHLNFKLKYSRFSIIFQFFIGLSLAVLFYQLMPLLWWLVVISLLFISFIFFLKRPQLAQIAYLDKKLWSLAYKSQNTV
SRVKILKIIDCQIFIVIYFEGHKTLTSIIWFDQMSLAEWKKLKTLEKLY

Download         Length: 390 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10318.77 Da        Isoelectric Point: 4.6150

>AT276421 WP_001288210.1 NZ_CP121567:c79953-79696 [Acinetobacter baumannii]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A7U4BQM7

References