Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2067778..2068049 Replicon chromosome
Accession NC_017664
Organism Escherichia coli W

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2067816..2067919 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2067778..2068049 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
WFL_RS10285 2064935..2066374 + 1440 WP_001307251.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
WFL_RS10290 2066492..2066728 + 237 WP_001295499.1 DUF1480 family protein -
WFL_RS10295 2066833..2067024 + 192 WP_001296140.1 YebW family protein -
WFL_RS10300 2067025..2067681 - 657 WP_000812724.1 protein-serine/threonine phosphatase -
- 2067778..2068049 + 272 - - Antitoxin
- 2067816..2067919 - 104 - - Toxin
WFL_RS10310 2068077..2068418 - 342 WP_000976472.1 YebY family protein -
WFL_RS10315 2068431..2069303 - 873 WP_000879282.1 copper homeostasis membrane protein CopD -
WFL_RS10320 2069307..2069681 - 375 WP_000204699.1 CopC domain-containing protein YobA -
WFL_RS10325 2069820..2070050 + 231 WP_000916763.1 DNA polymerase III subunit theta -
WFL_RS10330 2070152..2070808 + 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
WFL_RS10335 2070832..2071494 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T27642 NC_017664:c2067919-2067816 [Escherichia coli W]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT27642 NC_017664:2067778-2068049 [Escherichia coli W]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References