Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 79307..79960 Replicon chromosome
Accession NZ_CP121563
Organism Acinetobacter baumannii strain RAB94

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag MTS31_RS00410 Protein ID WP_000607077.1
Coordinates 79307..79696 (-) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID V5V966
Locus tag MTS31_RS00415 Protein ID WP_001288210.1
Coordinates 79703..79960 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MTS31_RS00395 (MTS31_00395) 74425..76620 - 2196 WP_001158906.1 TRAP transporter large permease subunit -
MTS31_RS00400 (MTS31_00400) 76808..77374 - 567 WP_000651538.1 rhombosortase -
MTS31_RS00405 (MTS31_00405) 77452..78537 - 1086 WP_000049106.1 hypothetical protein -
MTS31_RS00410 (MTS31_00410) 79307..79696 - 390 WP_000607077.1 membrane protein Toxin
MTS31_RS00415 (MTS31_00415) 79703..79960 - 258 WP_001288210.1 succinate dehydrogenase assembly factor 2 Antitoxin
MTS31_RS00420 (MTS31_00420) 80148..81320 + 1173 WP_001190542.1 acyl-CoA dehydrogenase family protein -
MTS31_RS00425 (MTS31_00425) 81369..82859 - 1491 WP_000415125.1 NAD(P)/FAD-dependent oxidoreductase -
MTS31_RS00430 (MTS31_00430) 83041..83418 - 378 WP_001216380.1 50S ribosomal protein L17 -
MTS31_RS00435 (MTS31_00435) 83437..84444 - 1008 WP_000198631.1 DNA-directed RNA polymerase subunit alpha -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(10-82)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15552.88 Da        Isoelectric Point: 10.4313

>T276418 WP_000607077.1 NZ_CP121563:c79696-79307 [Acinetobacter baumannii]
MINHLNFKLKYSRFSIIFQFFIGLSLAVLFYQLMPLLWWLVVISLLFISFIFFLKRPQLAQIAYLDKKLWSLAYKSQNTV
SRVKILKIIDCQIFIVIYFEGHKTLTSIIWFDQMSLAEWKKLKTLEKLY

Download         Length: 390 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10318.77 Da        Isoelectric Point: 4.6150

>AT276418 WP_001288210.1 NZ_CP121563:c79960-79703 [Acinetobacter baumannii]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A7U4BQM7

References