Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 3933850..3934503 Replicon chromosome
Accession NZ_CP121560
Organism Acinetobacter baumannii strain RAB97

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag MTS88_RS19275 Protein ID WP_000607077.1
Coordinates 3934114..3934503 (+) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID V5V966
Locus tag MTS88_RS19270 Protein ID WP_001288210.1
Coordinates 3933850..3934107 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MTS88_RS19250 (MTS88_19250) 3929366..3930373 + 1008 WP_000198631.1 DNA-directed RNA polymerase subunit alpha -
MTS88_RS19255 (MTS88_19255) 3930392..3930769 + 378 WP_001216380.1 50S ribosomal protein L17 -
MTS88_RS19260 (MTS88_19260) 3930951..3932441 + 1491 WP_000415125.1 NAD(P)/FAD-dependent oxidoreductase -
MTS88_RS19265 (MTS88_19265) 3932490..3933662 - 1173 WP_001190542.1 acyl-CoA dehydrogenase family protein -
MTS88_RS19270 (MTS88_19270) 3933850..3934107 + 258 WP_001288210.1 succinate dehydrogenase assembly factor 2 Antitoxin
MTS88_RS19275 (MTS88_19275) 3934114..3934503 + 390 WP_000607077.1 membrane protein Toxin
MTS88_RS19280 (MTS88_19280) 3935273..3936358 + 1086 WP_000049106.1 hypothetical protein -
MTS88_RS19285 (MTS88_19285) 3936436..3937002 + 567 WP_000651538.1 rhombosortase -
MTS88_RS19290 (MTS88_19290) 3937190..3939385 + 2196 WP_001158906.1 TRAP transporter large permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(10-82)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15552.88 Da        Isoelectric Point: 10.4313

>T276415 WP_000607077.1 NZ_CP121560:3934114-3934503 [Acinetobacter baumannii]
MINHLNFKLKYSRFSIIFQFFIGLSLAVLFYQLMPLLWWLVVISLLFISFIFFLKRPQLAQIAYLDKKLWSLAYKSQNTV
SRVKILKIIDCQIFIVIYFEGHKTLTSIIWFDQMSLAEWKKLKTLEKLY

Download         Length: 390 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10318.77 Da        Isoelectric Point: 4.6150

>AT276415 WP_001288210.1 NZ_CP121560:3933850-3934107 [Acinetobacter baumannii]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A7U4BQM7

References