Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) BrnTA/BrnT-BrnA
Location 557..1145 Replicon plasmid pII_RAB9
Accession NZ_CP121558
Organism Acinetobacter baumannii strain RAB9

Toxin (Protein)


Gene name brnT Uniprot ID A0A3G6Z3M6
Locus tag MTS96_RS18515 Protein ID WP_000438826.1
Coordinates 557..844 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name brnA Uniprot ID N9M5I3
Locus tag MTS96_RS18520 Protein ID WP_001983304.1
Coordinates 831..1145 (+) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MTS96_RS18515 (MTS96_18515) 557..844 + 288 WP_000438826.1 BrnT family toxin Toxin
MTS96_RS18520 (MTS96_18520) 831..1145 + 315 WP_001983304.1 BrnA antitoxin family protein Antitoxin
MTS96_RS18525 (MTS96_18525) 1273..3684 + 2412 WP_000932953.1 TonB-dependent receptor ZnuD2 -
MTS96_RS18530 (MTS96_18530) 3989..4450 + 462 WP_000761346.1 DIP1984 family protein -
MTS96_RS18535 (MTS96_18535) 4773..4946 - 174 WP_001282484.1 hypothetical protein -
MTS96_RS18540 (MTS96_18540) 4946..5317 - 372 WP_000504218.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..17462 17462


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(7-88)

Antitoxin

BrnA antitoxin of type II toxin-antitoxin system

(41-96)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11303.72 Da        Isoelectric Point: 6.0889

>T276413 WP_000438826.1 NZ_CP121558:557-844 [Acinetobacter baumannii]
MEQYFEWDEAKNRKNQKKHDISFETASLVFEDPLRISIQDRHTNGEERWQTIGRVKGVLMLLVAHTIFDEDDCEIIRIIS
ARQVTKAERNKYEHG

Download         Length: 288 bp

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 12208.84 Da        Isoelectric Point: 7.2026

>AT276413 WP_001983304.1 NZ_CP121558:831-1145 [Acinetobacter baumannii]
MSMVRYSHKELNEKFGEKQDAEIQRLLAKGTVPDDQLDLSDIPEITDWSNAVRQNQFYRPVKQQTSIRLDADVLAWFKAQ
GKGYQTRMNEILRDAMLKELKNHQ

Download         Length: 315 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3G6Z3M6

Antitoxin

Source ID Structure
AlphaFold DB N9M5I3

References