Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type IV Classification (family/domain) cptAB/-
Location 1020510..1021163 Replicon chromosome
Accession NZ_CP121557
Organism Acinetobacter baumannii strain RAB9

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag MTS96_RS04700 Protein ID WP_000607077.1
Coordinates 1020510..1020899 (-) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID V5V966
Locus tag MTS96_RS04705 Protein ID WP_001288210.1
Coordinates 1020906..1021163 (-) Length 86 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MTS96_RS04685 (MTS96_04685) 1015628..1017823 - 2196 WP_001158906.1 TRAP transporter large permease subunit -
MTS96_RS04690 (MTS96_04690) 1018011..1018577 - 567 WP_000651538.1 rhombosortase -
MTS96_RS04695 (MTS96_04695) 1018655..1019740 - 1086 WP_000049106.1 hypothetical protein -
MTS96_RS04700 (MTS96_04700) 1020510..1020899 - 390 WP_000607077.1 membrane protein Toxin
MTS96_RS04705 (MTS96_04705) 1020906..1021163 - 258 WP_001288210.1 succinate dehydrogenase assembly factor 2 Antitoxin
MTS96_RS04710 (MTS96_04710) 1021351..1022523 + 1173 WP_001190542.1 acyl-CoA dehydrogenase family protein -
MTS96_RS04715 (MTS96_04715) 1022572..1024062 - 1491 WP_000415125.1 NAD(P)/FAD-dependent oxidoreductase -
MTS96_RS04720 (MTS96_04720) 1024244..1024621 - 378 WP_001216380.1 50S ribosomal protein L17 -
MTS96_RS04725 (MTS96_04725) 1024640..1025647 - 1008 WP_000198631.1 DNA-directed RNA polymerase subunit alpha -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

(10-82)


Sequences


Toxin        


Download         Length: 130 a.a.        Molecular weight: 15552.88 Da        Isoelectric Point: 10.4313

>T276412 WP_000607077.1 NZ_CP121557:c1020899-1020510 [Acinetobacter baumannii]
MINHLNFKLKYSRFSIIFQFFIGLSLAVLFYQLMPLLWWLVVISLLFISFIFFLKRPQLAQIAYLDKKLWSLAYKSQNTV
SRVKILKIIDCQIFIVIYFEGHKTLTSIIWFDQMSLAEWKKLKTLEKLY

Download         Length: 390 bp


Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10318.77 Da        Isoelectric Point: 4.6150

>AT276412 WP_001288210.1 NZ_CP121557:c1021163-1020906 [Acinetobacter baumannii]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG

Download         Length: 258 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure
AlphaFold DB A0A7U4BQM7

References