Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tsbAT/-
Location 1736568..1737370 Replicon chromosome
Accession NZ_CP121509
Organism Staphylococcus epidermidis strain 21FSE01

Toxin (Protein)


Gene name tsbT Uniprot ID -
Locus tag QA595_RS07940 Protein ID WP_070817515.1
Coordinates 1736568..1736747 (-) Length 60 a.a.

Antitoxin (Protein)


Gene name tsbA Uniprot ID -
Locus tag QA595_RS07945 Protein ID WP_002486232.1
Coordinates 1736771..1737370 (-) Length 200 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QA595_RS07920 1731961..1733094 - 1134 WP_001829819.1 GAF domain-containing sensor histidine kinase -
QA595_RS07925 1733253..1734077 + 825 WP_001829804.1 RluA family pseudouridine synthase -
QA595_RS07930 1734438..1735823 - 1386 WP_001829862.1 class II fumarate hydratase -
QA595_RS07935 1736008..1736412 - 405 WP_001829818.1 hypothetical protein -
QA595_RS07940 1736568..1736747 - 180 WP_070817515.1 SAS053 family protein Toxin
QA595_RS07945 1736771..1737370 - 600 WP_002486232.1 glucosamine-6-phosphate isomerase Antitoxin
QA595_RS07950 1737528..1737998 - 471 WP_001829836.1 tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL -
QA595_RS07955 1737995..1739125 - 1131 WP_001829814.1 tRNA epoxyqueuosine(34) reductase QueG -
QA595_RS07960 1739340..1739489 - 150 WP_002468809.1 hypothetical protein -
QA595_RS07965 1739986..1740708 - 723 WP_001829838.1 amino acid ABC transporter ATP-binding protein -
QA595_RS07970 1740701..1742158 - 1458 WP_002440300.1 ABC transporter substrate-binding protein/permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Glucosamine-6-phosphate isomerase

(130-195)


Sequences

Toxin        


Download         Length: 60 a.a.        Molecular weight: 6949.53 Da        Isoelectric Point: 4.2904

>T276384 WP_070817515.1 NZ_CP121509:c1736747-1736568 [Staphylococcus epidermidis]
MANKKDSKLNYHEEENAMVTDLDDLKELGKEMEQISQENDEEKLNQSHDNDVRSDLKKQ

Download         Length: 180 bp

Antitoxin


Download         Length: 200 a.a.        Molecular weight: 22695.55 Da        Isoelectric Point: 4.8641

>AT276384 WP_002486232.1 NZ_CP121509:c1737370-1736771 [Staphylococcus epidermidis]
MAMNFKVFDNSEKVAEYTADILRKQFNNNPTTIAGFHLSKEHAPVFDELKKNVENHTVDFSQINILDYDDNHSYYEALGV
PTGQIYSISYENDAIDFISDKIKTKENKGKLTMQVLTIDENGNLDISVRQGLMEAREIFLVITGANKRDMVEKLYRENGK
TSFEPSDLKAHRMVNVILDKEAAAGLPEDVKEYFTARFA

Download         Length: 600 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References