Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /Acetyltransf_4(toxin)
Location 4001518..4002920 Replicon chromosome
Accession NZ_CP121476
Organism Pseudomonas sp. 905_Psudmo1

Toxin (Protein)


Gene name - Uniprot ID A0A1H2LZG4
Locus tag P9K38_RS18655 Protein ID WP_017675066.1
Coordinates 4002351..4002920 (-) Length 190 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag P9K38_RS18650 Protein ID WP_021490280.1
Coordinates 4001518..4002345 (-) Length 276 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P9K38_RS18635 (P9K38_18635) 3998423..3999328 - 906 WP_112210251.1 GIDE domain-containing protein -
P9K38_RS18640 (P9K38_18640) 3999339..3999911 - 573 WP_017675063.1 LemA family protein -
P9K38_RS18645 (P9K38_18645) 4000102..4001439 + 1338 WP_278325291.1 imelysin family protein -
P9K38_RS18650 (P9K38_18650) 4001518..4002345 - 828 WP_021490280.1 AraC family transcriptional regulator Antitoxin
P9K38_RS18655 (P9K38_18655) 4002351..4002920 - 570 WP_017675066.1 GNAT family protein Toxin
P9K38_RS18660 (P9K38_18660) 4003137..4006625 + 3489 WP_092376995.1 PAS domain-containing hybrid sensor histidine kinase/response regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(14-146)

Antitoxin

DNA binding HTH domain, AraC-type

(193-270)


Sequences

Toxin        


Download         Length: 190 a.a.        Molecular weight: 21372.59 Da        Isoelectric Point: 8.0477

>T276353 WP_017675066.1 NZ_CP121476:c4002920-4002351 [Pseudomonas sp. 905_Psudmo1]
MFKPQLVTLQRGALRLEPLSDADIPALVALAEANREELLYMSGTQRLDWYRSALADMREQRALPFVIRLGDELVGTTRFA
DFMNTLPACEIGWTWLDRGQHGSGLNTSIKYLMLKHAFENWGMVRVQLKTAASNLRSQRAIEKLGAVREGLLRNHRRLAD
GRLDDTVLYSITDLEWPALRGAMEAGFNA

Download         Length: 570 bp

Antitoxin


Download         Length: 276 a.a.        Molecular weight: 30750.13 Da        Isoelectric Point: 8.7310

>AT276353 WP_021490280.1 NZ_CP121476:c4002345-4001518 [Pseudomonas sp. 905_Psudmo1]
MHSREQTRFWQASALSGVELLQARYLEQRFAPHVHEGFVFTVIEHGAQRFRHRGCDHLAPQGSMVLINPDEVHTGSKAHE
DGWRYRGFYPDNAQVLGALQELGLAKAGMPSFAFSVLHDPRLHAAFLQLHQLLEGGAEALQQQLAWREAILLLFQHHAQL
AEPPAPGREPWAVACAKQMLAERLVEPPSLEELAAAVNLSPFHFARVFRRATGLPPHAWLKQRRLEQARALLKTGCTAVA
VAMQLGFADQSHLSRQFKQVYGVSPGEYRSAVARS

Download         Length: 828 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1H2LZG4

Antitoxin

Source ID Structure

References