Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hipBA/HipA-couple_hipB
Location 2752114..2753709 Replicon chromosome
Accession NZ_CP121476
Organism Pseudomonas sp. 905_Psudmo1

Toxin (Protein)


Gene name hipA Uniprot ID -
Locus tag P9K38_RS12930 Protein ID WP_278324786.1
Coordinates 2752384..2753709 (-) Length 442 a.a.

Antitoxin (Protein)


Gene name hipB Uniprot ID A0A1G5YAZ4
Locus tag P9K38_RS12925 Protein ID WP_017676963.1
Coordinates 2752114..2752383 (-) Length 90 a.a.

Genomic Context

P9K38_RS12920P9K38_RS12935P9K38_RS12940P9K38_RS12945P9K38_RS12955P9K38_RS12925P9K38_RS12930P9K38_RS12950
Location: 2750609..2751673 (1065 bp)
Type: Others
Protein ID: WP_278324784.1
Location: 2753965..2754171 (207 bp)
Type: Others
Protein ID: WP_278326890.1
Location: 2754280..2755422 (1143 bp)
Type: Others
Protein ID: WP_278324787.1
Location: 2755457..2756029 (573 bp)
Type: Others
Protein ID: WP_003460252.1
Location: 2757192..2757959 (768 bp)
Type: Others
Protein ID: WP_064494771.1
Location: 2752114..2752383 (270 bp)
Type: Antitoxin
Protein ID: WP_017676963.1
Location: 2752384..2753709 (1326 bp)
Type: Toxin
Protein ID: WP_278324786.1
Location: 2756129..2757091 (963 bp)
Type: Others
Protein ID: WP_039964599.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
P9K38_RS12920 (P9K38_12920)2750609..2751673+1065WP_278324784.1type VI secretion system protein TssA-
P9K38_RS12925 (P9K38_12925)2752114..2752383-270WP_017676963.1helix-turn-helix domain-containing proteinAntitoxin
P9K38_RS12930 (P9K38_12930)2752384..2753709-1326WP_278324786.1HipA domain-containing proteinToxin
P9K38_RS12935 (P9K38_12935)2753965..2754171+207WP_278326890.1hypothetical protein-
P9K38_RS12940 (P9K38_12940)2754280..2755422+1143WP_278324787.1elongation factor P maturation arginine rhamnosyltransferase EarP-
P9K38_RS12945 (P9K38_12945)2755457..2756029+573WP_003460252.1elongation factor P-
P9K38_RS12950 (P9K38_12950)2756129..2757091-963WP_039964599.1LysR family transcriptional regulator-
P9K38_RS12955 (P9K38_12955)2757192..2757959+768WP_064494771.1sulfite exporter TauE/SafE family protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HipA-like, C-terminal

(166-380)

Antitoxin

Cro/C1-type helix-turn-helix domain

(25-69)


Sequences

Toxin        


Download         Length: 442 a.a.        Molecular weight: 49158.53 Da        Isoelectric Point: 5.8080

>T276351 WP_278324786.1 NZ_CP121476:c2753709-2752384 [Pseudomonas sp. 905_Psudmo1]
MHSLTLQLYSGHAWHDAMHLNFEQPEAGLAGSCSFGYEQAYLLETLEHIGSRLEHAVSVTVPLDWESYRASEAPAFLHDI
LPAGAARRFLIQRLGDQKPENLGLDLFLLSRCAPAPVGNLRIKEAAAALQESPLLGFSREDVINRDARFLEYAYEQGAAI
GGATGAGGEAPKLLLTEDREGALHPDAALPDESATRHWFVKFARNQARQTDQDILRSEFCYYRAIQRLGLDTVPAEGLAL
EEGRKPSLWMHRFDRHLSAAGVERSAMESLYSLAGVTVPGSYLLHTDVLHHLVRLWQKTGQGAQVGDMIFEYLQRDLLNQ
ILGNSDNHGRNTSILRNSTGLKLAPIYDLAPMVMDDEGVTRTTKWPQSIEIAGEVNWRQACAALAQWTDADVLYERLRGS
AQDFLALPDLLSDQGLPNSTMNHPRIALRTLHQRLNRWELV

Download         Length: 1326 bp

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 10104.75 Da        Isoelectric Point: 10.7429

>AT276351 WP_017676963.1 NZ_CP121476:c2752383-2752114 [Pseudomonas sp. 905_Psudmo1]
MDIIERNRILTEIQTQLASGELTIGQAVRKLRKEITGLQQARFAQMCKLSLRALRQLEHDESNPTVQTLNSVFNPFGMQV
GIVPKSRIQ

Download         Length: 270 bp


Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A1G5YAZ4

References