Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-dnstrm_HI1420
Location 1522794..1523389 Replicon chromosome
Accession NZ_CP121464
Organism Janthinobacterium rivuli strain DEMB2

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag P9875_RS06825 Protein ID WP_035828697.1
Coordinates 1523090..1523389 (-) Length 100 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag P9875_RS06820 Protein ID WP_035825229.1
Coordinates 1522794..1523090 (-) Length 99 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P9875_RS06800 (P9875_06800) 1518255..1518704 - 450 WP_035825219.1 hypothetical protein -
P9875_RS06805 (P9875_06805) 1518964..1519623 - 660 WP_278317905.1 FxDxF family PEP-CTERM protein -
P9875_RS06810 (P9875_06810) 1519925..1522030 - 2106 WP_278317906.1 TonB-dependent siderophore receptor -
P9875_RS06815 (P9875_06815) 1522319..1522765 + 447 WP_176388863.1 response regulator -
P9875_RS06820 (P9875_06820) 1522794..1523090 - 297 WP_035825229.1 putative addiction module antidote protein Antitoxin
P9875_RS06825 (P9875_06825) 1523090..1523389 - 300 WP_035828697.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
P9875_RS06835 (P9875_06835) 1523812..1524657 - 846 WP_099400788.1 glutamate racemase -
P9875_RS06840 (P9875_06840) 1524723..1526264 - 1542 WP_034784516.1 fumarate hydratase -
P9875_RS06845 (P9875_06845) 1526346..1526963 - 618 WP_099400789.1 YqhA family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(2-96)

Antitoxin

Uncharacterized protein HI1420

(4-95)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11097.66 Da        Isoelectric Point: 8.5106

>T276347 WP_035828697.1 NZ_CP121464:c1523389-1523090 [Janthinobacterium rivuli]
VKSIHTTATFDDWFSQLKDRKAFFRIQARIDRAEDGNFGDCKPVGGGVSEMRIDCGPGYRVYFTQRGMEIIILLAGGDKS
TQAKDIKTAQRLAQILQEV

Download         Length: 300 bp

Antitoxin


Download         Length: 99 a.a.        Molecular weight: 10600.04 Da        Isoelectric Point: 5.6851

>AT276347 WP_035825229.1 NZ_CP121464:c1523090-1522794 [Janthinobacterium rivuli]
MIQKLNKWDSAQHLKTEEDIVAYFEACLEEAGDDASFIAKALGNIAKARGMTQLAKDTGLGRESLYKALSGEGNPSFDTI
LKVTHALGLQFRAAALNT

Download         Length: 297 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References