Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/StbC(antitoxin)
Location 1285107..1285745 Replicon chromosome
Accession NZ_CP121464
Organism Janthinobacterium rivuli strain DEMB2

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag P9875_RS05855 Protein ID WP_278317814.1
Coordinates 1285329..1285745 (+) Length 139 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag P9875_RS05850 Protein ID WP_278317813.1
Coordinates 1285107..1285316 (+) Length 70 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P9875_RS05835 (P9875_05835) 1282449..1283687 + 1239 WP_278317810.1 bifunctional glutamate N-acetyltransferase/amino-acid acetyltransferase ArgJ -
P9875_RS05840 (P9875_05840) 1283684..1284565 + 882 WP_278317811.1 ATP-binding protein -
P9875_RS05845 (P9875_05845) 1284562..1284984 + 423 WP_278317812.1 NUDIX domain-containing protein -
P9875_RS05850 (P9875_05850) 1285107..1285316 + 210 WP_278317813.1 DNA-binding protein Antitoxin
P9875_RS05855 (P9875_05855) 1285329..1285745 + 417 WP_278317814.1 hypothetical protein Toxin
P9875_RS05860 (P9875_05860) 1285769..1285960 - 192 WP_034748814.1 DNA gyrase inhibitor YacG -
P9875_RS05865 (P9875_05865) 1285979..1286734 - 756 WP_035824877.1 cell division protein ZapD -
P9875_RS05870 (P9875_05870) 1286797..1287444 - 648 WP_278317815.1 dephospho-CoA kinase -
P9875_RS05875 (P9875_05875) 1287467..1288336 - 870 WP_278317816.1 A24 family peptidase -
P9875_RS05880 (P9875_05880) 1288443..1289639 - 1197 WP_278317817.1 type II secretion system F family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 14844.25 Da        Isoelectric Point: 6.2201

>T276346 WP_278317814.1 NZ_CP121464:1285329-1285745 [Janthinobacterium rivuli]
MPGYLLDADVIVAARKGGAVPAGVAGFFERVAPEMRYVPVQVIAQLRAGIQCSWRREAALEALALEGWLEAVLAEYAPRL
LEFDLDCALVCARLHGRGHAHGVDRQIAAMGIAYGLTVVSGRLDSFAAQGLRLENPFI

Download         Length: 417 bp

Antitoxin


Download         Length: 70 a.a.        Molecular weight: 7944.13 Da        Isoelectric Point: 6.7248

>AT276346 WP_278317813.1 NZ_CP121464:1285107-1285316 [Janthinobacterium rivuli]
MPLTLTFTDIDELLIAALHKRARAHGRSIEDEHRDILRSALRPLPKRPLDDILRSMPDVGLDADFERRS

Download         Length: 210 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References