Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PP_4151-4152/excise(antitoxin)
Location 497421..498463 Replicon chromosome
Accession NZ_CP121464
Organism Janthinobacterium rivuli strain DEMB2

Toxin (Protein)


Gene name PP_4152 Uniprot ID -
Locus tag P9875_RS02195 Protein ID WP_099401173.1
Coordinates 497885..498463 (+) Length 193 a.a.

Antitoxin (Protein)


Gene name PP_4151 Uniprot ID A0A2G3LJ42
Locus tag P9875_RS02190 Protein ID WP_035823639.1
Coordinates 497421..497885 (+) Length 155 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P9875_RS02175 (P9875_02175) 494225..496294 + 2070 WP_035823635.1 M13-type metalloendopeptidase -
P9875_RS02180 (P9875_02180) 496433..496993 - 561 WP_035823637.1 c-type cytochrome -
P9875_RS02190 (P9875_02190) 497421..497885 + 465 WP_035823639.1 helix-turn-helix domain-containing protein Antitoxin
P9875_RS02195 (P9875_02195) 497885..498463 + 579 WP_099401173.1 PIN domain-containing protein Toxin
P9875_RS02200 (P9875_02200) 498748..501405 + 2658 WP_278317471.1 TonB-dependent receptor -
P9875_RS02205 (P9875_02205) 501515..502867 + 1353 WP_099401175.1 MFS transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(9-116)

Antitoxin

Helix-turn-helix domain, group 17

(85-132)


Sequences

Toxin        


Download         Length: 193 a.a.        Molecular weight: 21152.39 Da        Isoelectric Point: 4.8673

>T276345 WP_099401173.1 NZ_CP121464:497885-498463 [Janthinobacterium rivuli]
MAGYHRYTAVLDACVLYPASLRDLLLSLAADGIFSARWTAQIQEEWQRNLLLKRPDLDPSALARTSALMAEAVEDGVIES
YEYLIDALVLPDADDRHVLAAAIVGHADAIVTFNLKDLPDAIMRGHNIEVLHPDDFLVAQYELAPIRTLSVVKENRALLR
KPTRSAAELIATYEAQGLPQLGKLLRSAIALL

Download         Length: 579 bp

Antitoxin


Download         Length: 155 a.a.        Molecular weight: 17333.91 Da        Isoelectric Point: 6.9810

>AT276345 WP_035823639.1 NZ_CP121464:497421-497885 [Janthinobacterium rivuli]
MSNVIDRLENKEDLELAKAAQRCLVSALDHSRAVQIAVLEEGAQDLGDAPLLRLPPNVLRLFADVLGTLAQGKAVTVMPK
EHDVTTQEAAMYLNMSRPYLVRLLEAGKIPHHKVGTHRRLRFEDVVQYKDERKRRSQQALQALADQAQELELGY

Download         Length: 465 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A2G3LJ42

References