Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) parDE/RHH(antitoxin)
Location 2975959..2976476 Replicon chromosome
Accession NZ_CP121463
Organism Arthrobacter sp. Y-9

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag P9849_RS13470 Protein ID WP_278267242.1
Coordinates 2976189..2976476 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag P9849_RS13465 Protein ID WP_278267241.1
Coordinates 2975959..2976192 (+) Length 78 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P9849_RS13445 (P9849_13445) 2973092..2973766 + 675 WP_278267237.1 response regulator -
P9849_RS13450 (P9849_13450) 2973822..2974472 + 651 WP_278267238.1 HAD-IA family hydrolase -
P9849_RS13455 (P9849_13455) 2974499..2975056 + 558 WP_278267239.1 N-acetyltransferase -
P9849_RS13460 (P9849_13460) 2975042..2975839 - 798 WP_278267240.1 SDR family oxidoreductase -
P9849_RS13465 (P9849_13465) 2975959..2976192 + 234 WP_278267241.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
P9849_RS13470 (P9849_13470) 2976189..2976476 + 288 WP_278267242.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
P9849_RS13475 (P9849_13475) 2976502..2976807 - 306 WP_278267243.1 hypothetical protein -
P9849_RS13480 (P9849_13480) 2976884..2977882 - 999 WP_278267244.1 glycosyltransferase family 4 protein -
P9849_RS13485 (P9849_13485) 2977879..2978271 - 393 WP_278267245.1 6-carboxytetrahydropterin synthase -
P9849_RS13490 (P9849_13490) 2978274..2979281 - 1008 WP_278267246.1 dehydrogenase -
P9849_RS13495 (P9849_13495) 2979411..2980634 - 1224 WP_278267247.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(4-90)

Antitoxin

(1-76)


Sequences


Toxin        


Download         Length: 96 a.a.        Molecular weight: 10951.40 Da        Isoelectric Point: 7.3566

>T276344 WP_278267242.1 NZ_CP121463:2976189-2976476 [Arthrobacter sp. Y-9]
MSFRLTPAARADLSSIWDYTAERWDTRQAETYIRELHAAMERIAEDPARGRTCDEIRAGYRKYAIGSHLIFYVVAADGVD
VIRVLHQRMDAGRHL

Download         Length: 288 bp


Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8263.16 Da        Isoelectric Point: 4.8041

>AT276344 WP_278267241.1 NZ_CP121463:2975959-2976192 [Arthrobacter sp. Y-9]
MSSNTSISLDEHSAAFLAREVKSGRFRTASEAVRAGLRLLEDQETHLAALRASLAEGESSGTPEPFDLEAFIAEKKG

Download         Length: 234 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References