276342

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higB-toxA/Tad-couple_hipB
Location 6211799..6212475 Replicon chromosome
Accession NZ_CP121445
Organism Anaerocolumna sp. AGMB13025

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag QA584_RS25985 Protein ID WP_278272004.1
Coordinates 6211799..6212164 (+) Length 122 a.a.

Antitoxin (Protein)


Gene name toxA Uniprot ID -
Locus tag QA584_RS25990 Protein ID WP_278272005.1
Coordinates 6212161..6212475 (+) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QA584_RS25955 (QA584_25955) 6207412..6207633 - 222 WP_278271998.1 hypothetical protein -
QA584_RS25960 (QA584_25960) 6208001..6208540 - 540 WP_278271999.1 RNA 2'-phosphotransferase -
QA584_RS25965 (QA584_25965) 6208542..6208691 - 150 WP_278272000.1 hypothetical protein -
QA584_RS25970 (QA584_25970) 6209031..6209243 - 213 WP_278272001.1 hypothetical protein -
QA584_RS25975 (QA584_25975) 6209257..6209559 - 303 WP_278272002.1 hypothetical protein -
QA584_RS25980 (QA584_25980) 6209574..6211133 - 1560 WP_278272003.1 EndoU domain-containing protein -
QA584_RS25985 (QA584_25985) 6211799..6212164 + 366 WP_278272004.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QA584_RS25990 (QA584_25990) 6212161..6212475 + 315 WP_278272005.1 helix-turn-helix transcriptional regulator Antitoxin
QA584_RS25995 (QA584_25995) 6213440..6214078 - 639 WP_278272006.1 hypothetical protein -
QA584_RS26000 (QA584_26000) 6214075..6215589 - 1515 WP_278272007.1 hypothetical protein -
QA584_RS26005 (QA584_26005) 6216028..6216414 - 387 WP_278272008.1 hypothetical protein -
QA584_RS26010 (QA584_26010) 6216614..6217402 - 789 WP_278272009.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(36-112)

Antitoxin

Cro/C1-type helix-turn-helix domain

(40-93)


Sequences

Toxin        


Download         Length: 122 a.a.        Molecular weight: 14515.79 Da        Isoelectric Point: 10.3714

>T276342 WP_278272004.1 NZ_CP121445:6211799-6212164 [Anaerocolumna sp. AGMB13025]
MFKVIFYKDKSGNEPIKDFLLELSQKAQANKNDRIQFNKISAYIKALQTYGTRIGKPTVKHIDGDLWELRPLENRIFFFY
WRDNTFVLLHHFIKKSQKTPTKEIEQARANLKDFLERIDHK

Download         Length: 366 bp

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11458.32 Da        Isoelectric Point: 5.1088

>AT276342 WP_278272005.1 NZ_CP121445:6212161-6212475 [Anaerocolumna sp. AGMB13025]
MSIKVGNTNFTEFDDLYNDPNIVPPAERAKIDFEVALIGKLIEARETKGLSQKQLADLAGLKQPAIARLESMKATPQIDT
LFKILQPLGYTLAVVPVEKPPQQP

Download         Length: 315 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References