Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yoeB-relB/YoeB-RelB
Location 111236..111749 Replicon chromosome
Accession NZ_CP121375
Organism Acinetobacter baumannii strain LRT

Toxin (Protein)


Gene name yoeB Uniprot ID A0A2L2M0A2
Locus tag P9J63_RS00540 Protein ID WP_000203952.1
Coordinates 111236..111499 (-) Length 88 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID S7WSW9
Locus tag P9J63_RS00545 Protein ID WP_000557943.1
Coordinates 111486..111749 (-) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P9J63_RS00510 (P9J63_00510) 107311..108741 + 1431 WP_000178999.1 amino acid permease -
P9J63_RS00515 (P9J63_00515) 108799..109143 - 345 Protein_97 LysR substrate-binding domain-containing protein -
P9J63_RS00520 (P9J63_00520) 109182..110430 - 1249 Protein_98 IS3 family transposase -
P9J63_RS00525 (P9J63_00525) 110489..110800 - 312 WP_079281501.1 LysR substrate-binding domain-containing protein -
P9J63_RS00530 (P9J63_00530) 110940..111038 + 99 Protein_100 IS5/IS1182 family transposase -
P9J63_RS00535 (P9J63_00535) 111070..111177 - 108 Protein_101 transposase domain-containing protein -
P9J63_RS00540 (P9J63_00540) 111236..111499 - 264 WP_000203952.1 Txe/YoeB family addiction module toxin Toxin
P9J63_RS00545 (P9J63_00545) 111486..111749 - 264 WP_000557943.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
P9J63_RS00550 (P9J63_00550) 112165..115512 + 3348 WP_270893669.1 DEAD/DEAH box helicase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(8-87)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10664.10 Da        Isoelectric Point: 8.4894

>T276335 WP_000203952.1 NZ_CP121375:c111499-111236 [Acinetobacter baumannii]
MTSRNVEWTENAWDEYIYWQTQDKKILKRINTLIRECQRTPFEGTGKPEPLKANLSGFWSRRIDEKHRLVYEVTDERISI
IQCRFHY

Download         Length: 264 bp

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9841.04 Da        Isoelectric Point: 5.5940

>AT276335 WP_000557943.1 NZ_CP121375:c111749-111486 [Acinetobacter baumannii]
MHVFTYTDARNNLKSVLDKVIDDADVAFITRKEGGHAVVMGQDHYDSLMETLYLLSSPNNTTRLNESIAQLRAGKTKQRE
LIKDDES

Download         Length: 264 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2L2M0A2

Antitoxin

Source ID Structure
AlphaFold DB S7WSW9

References