Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 15162..15687 Replicon plasmid plas4_LRB
Accession NZ_CP121374
Organism Acinetobacter baumannii strain LRB

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag P9J61_RS19525 Protein ID WP_005130374.1
Coordinates 15400..15687 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag P9J61_RS19520 Protein ID WP_005130375.1
Coordinates 15162..15410 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P9J61_RS19495 (P9J61_19495) 12237..13151 - 915 WP_004843977.1 replication initiation protein RepM -
P9J61_RS19500 (P9J61_19500) 13602..14231 + 630 WP_005130378.1 AAA family ATPase -
P9J61_RS19505 (P9J61_19505) 14228..14467 + 240 WP_005130377.1 hypothetical protein -
P9J61_RS19510 (P9J61_19510) 14583..14651 + 69 Protein_11 helix-turn-helix domain-containing protein -
P9J61_RS19515 (P9J61_19515) 14734..15159 + 426 WP_005130376.1 hypothetical protein -
P9J61_RS19520 (P9J61_19520) 15162..15410 + 249 WP_005130375.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
P9J61_RS19525 (P9J61_19525) 15400..15687 + 288 WP_005130374.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
P9J61_RS19530 (P9J61_19530) 15848..15997 - 150 WP_079878061.1 DUF4113 domain-containing protein -
P9J61_RS19535 (P9J61_19535) 16490..17056 + 567 WP_004282045.1 recombinase family protein -
P9J61_RS19540 (P9J61_19540) 17231..17563 - 333 WP_005253224.1 hypothetical protein -
P9J61_RS19545 (P9J61_19545) 17594..18115 - 522 WP_109104475.1 hypothetical protein -
P9J61_RS19550 (P9J61_19550) 18619..19459 + 841 Protein_19 IS3 family transposase -
P9J61_RS19555 (P9J61_19555) 19705..20493 - 789 WP_004282048.1 OmpA family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..38300 38300


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(7-83)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11146.00 Da        Isoelectric Point: 10.1961

>T276334 WP_005130374.1 NZ_CP121374:15400-15687 [Acinetobacter baumannii]
MTYKLDFLEEALAEWNKLNPSIKQPLKKKLIKVLENPRIPKNKLPGHPNRYKIKLRSVGYRLVYEVIDDEVIFIVIAVGR
RENNAVYDEANSRHS

Download         Length: 288 bp

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9258.77 Da        Isoelectric Point: 5.0491

>AT276334 WP_005130375.1 NZ_CP121374:15162-15410 [Acinetobacter baumannii]
MTQLIHARMTASITELKKSPMDTVLAGKGEPVAILNRNIPAFYCVPADLYETMMEQLEDLELNKIADARANQKRIRVNID
DL

Download         Length: 249 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References