Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yoeB-relB/YoeB-RelB
Location 110336..110849 Replicon chromosome
Accession NZ_CP121370
Organism Acinetobacter baumannii strain LRB

Toxin (Protein)


Gene name yoeB Uniprot ID A0A2L2M0A2
Locus tag P9J61_RS00530 Protein ID WP_000203952.1
Coordinates 110336..110599 (-) Length 88 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID S7WSW9
Locus tag P9J61_RS00535 Protein ID WP_000557943.1
Coordinates 110586..110849 (-) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P9J61_RS00500 (P9J61_00500) 106411..107841 + 1431 WP_000178999.1 amino acid permease -
P9J61_RS00505 (P9J61_00505) 107899..108243 - 345 Protein_95 LysR substrate-binding domain-containing protein -
P9J61_RS00510 (P9J61_00510) 108282..109530 - 1249 Protein_96 IS3 family transposase -
P9J61_RS00515 (P9J61_00515) 109589..109900 - 312 WP_079281501.1 LysR substrate-binding domain-containing protein -
P9J61_RS00520 (P9J61_00520) 110040..110138 + 99 Protein_98 IS5/IS1182 family transposase -
P9J61_RS00525 (P9J61_00525) 110170..110277 - 108 Protein_99 transposase domain-containing protein -
P9J61_RS00530 (P9J61_00530) 110336..110599 - 264 WP_000203952.1 Txe/YoeB family addiction module toxin Toxin
P9J61_RS00535 (P9J61_00535) 110586..110849 - 264 WP_000557943.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
P9J61_RS00540 (P9J61_00540) 111265..114612 + 3348 WP_270893669.1 DEAD/DEAH box helicase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(8-87)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10664.10 Da        Isoelectric Point: 8.4894

>T276329 WP_000203952.1 NZ_CP121370:c110599-110336 [Acinetobacter baumannii]
MTSRNVEWTENAWDEYIYWQTQDKKILKRINTLIRECQRTPFEGTGKPEPLKANLSGFWSRRIDEKHRLVYEVTDERISI
IQCRFHY

Download         Length: 264 bp

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9841.04 Da        Isoelectric Point: 5.5940

>AT276329 WP_000557943.1 NZ_CP121370:c110849-110586 [Acinetobacter baumannii]
MHVFTYTDARNNLKSVLDKVIDDADVAFITRKEGGHAVVMGQDHYDSLMETLYLLSSPNNTTRLNESIAQLRAGKTKQRE
LIKDDES

Download         Length: 264 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2L2M0A2

Antitoxin

Source ID Structure
AlphaFold DB S7WSW9

References