Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 15004..15529 Replicon plasmid plas4_Ab_8_4
Accession NZ_CP121369
Organism Acinetobacter baumannii strain Ab_8_4

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag P9J59_RS19530 Protein ID WP_005130374.1
Coordinates 15242..15529 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag P9J59_RS19525 Protein ID WP_005130375.1
Coordinates 15004..15252 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P9J59_RS19500 (P9J59_19500) 12079..12993 - 915 WP_004843977.1 replication initiation protein RepM -
P9J59_RS19505 (P9J59_19505) 13444..14073 + 630 WP_005130378.1 AAA family ATPase -
P9J59_RS19510 (P9J59_19510) 14070..14309 + 240 WP_005130377.1 hypothetical protein -
P9J59_RS19515 (P9J59_19515) 14425..14493 + 69 Protein_12 helix-turn-helix domain-containing protein -
P9J59_RS19520 (P9J59_19520) 14576..15001 + 426 WP_005130376.1 hypothetical protein -
P9J59_RS19525 (P9J59_19525) 15004..15252 + 249 WP_005130375.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
P9J59_RS19530 (P9J59_19530) 15242..15529 + 288 WP_005130374.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
P9J59_RS19535 (P9J59_19535) 15690..15839 - 150 WP_079878061.1 DUF4113 domain-containing protein -
P9J59_RS19540 (P9J59_19540) 16332..16898 + 567 WP_004282045.1 recombinase family protein -
P9J59_RS19545 (P9J59_19545) 17073..17405 - 333 WP_005253224.1 hypothetical protein -
P9J59_RS19550 (P9J59_19550) 17436..17957 - 522 WP_109104475.1 hypothetical protein -
P9J59_RS19555 (P9J59_19555) 18461..19301 + 841 Protein_20 IS3 family transposase -
P9J59_RS19560 (P9J59_19560) 19547..20335 - 789 WP_004282048.1 OmpA family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..39272 39272


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(7-83)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11146.00 Da        Isoelectric Point: 10.1961

>T276328 WP_005130374.1 NZ_CP121369:15242-15529 [Acinetobacter baumannii]
MTYKLDFLEEALAEWNKLNPSIKQPLKKKLIKVLENPRIPKNKLPGHPNRYKIKLRSVGYRLVYEVIDDEVIFIVIAVGR
RENNAVYDEANSRHS

Download         Length: 288 bp

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9258.77 Da        Isoelectric Point: 5.0491

>AT276328 WP_005130375.1 NZ_CP121369:15004-15252 [Acinetobacter baumannii]
MTQLIHARMTASITELKKSPMDTVLAGKGEPVAILNRNIPAFYCVPADLYETMMEQLEDLELNKIADARANQKRIRVNID
DL

Download         Length: 249 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References