Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 3251579..3252232 Replicon chromosome
Accession NZ_CP121365
Organism Acinetobacter baumannii strain Ab_8_4

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag P9J59_RS15925 Protein ID WP_032036174.1
Coordinates 3251579..3251968 (-) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID V5V966
Locus tag P9J59_RS15930 Protein ID WP_001288210.1
Coordinates 3251975..3252232 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P9J59_RS15910 (P9J59_15910) 3247437..3249491 + 2055 WP_004839673.1 M3 family metallopeptidase -
P9J59_RS15915 (P9J59_15915) 3249532..3249741 + 210 WP_032037922.1 YheV family putative zinc ribbon protein -
P9J59_RS15920 (P9J59_15920) 3249860..3250792 - 933 WP_001040037.1 IS5-like element ISAha2 family transposase -
P9J59_RS15925 (P9J59_15925) 3251579..3251968 - 390 WP_032036174.1 membrane protein Toxin
P9J59_RS15930 (P9J59_15930) 3251975..3252232 - 258 WP_001288210.1 succinate dehydrogenase assembly factor 2 Antitoxin
P9J59_RS15935 (P9J59_15935) 3252420..3253592 + 1173 WP_031961342.1 acyl-CoA dehydrogenase family protein -
P9J59_RS15940 (P9J59_15940) 3253641..3255131 - 1491 WP_032036176.1 NAD(P)/FAD-dependent oxidoreductase -
P9J59_RS15945 (P9J59_15945) 3255313..3255690 - 378 WP_001216380.1 50S ribosomal protein L17 -
P9J59_RS15950 (P9J59_15950) 3255709..3256716 - 1008 WP_000198631.1 DNA-directed RNA polymerase subunit alpha -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 3249860..3250792 932


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(10-82)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15641.96 Da        Isoelectric Point: 10.5620

>T276325 WP_032036174.1 NZ_CP121365:c3251968-3251579 [Acinetobacter baumannii]
MINHLNFKLKYSRFSIIFQFFIGLSLAVLFYQLMPLLWWLVVISLLFISFIFFLKRPQLTQIAYLDKKLWSLAYQSQNTV
SRVKILKIIDYQIFIVIYFEGHKTLTSIIWFDQMSLAKWKKLKTLEKLY

Download         Length: 390 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10318.77 Da        Isoelectric Point: 4.6150

>AT276325 WP_001288210.1 NZ_CP121365:c3252232-3251975 [Acinetobacter baumannii]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A7U4BQM7

References