Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yoeB-relB/YoeB-RelB
Location 110354..110867 Replicon chromosome
Accession NZ_CP121365
Organism Acinetobacter baumannii strain Ab_8_4

Toxin (Protein)


Gene name yoeB Uniprot ID A0A2L2M0A2
Locus tag P9J59_RS00530 Protein ID WP_000203952.1
Coordinates 110354..110617 (-) Length 88 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID S7WSW9
Locus tag P9J59_RS00535 Protein ID WP_000557943.1
Coordinates 110604..110867 (-) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P9J59_RS00500 (P9J59_00500) 106429..107859 + 1431 WP_000178999.1 amino acid permease -
P9J59_RS00505 (P9J59_00505) 107917..108261 - 345 Protein_95 LysR substrate-binding domain-containing protein -
P9J59_RS00510 (P9J59_00510) 108300..109548 - 1249 Protein_96 IS3 family transposase -
P9J59_RS00515 (P9J59_00515) 109607..109918 - 312 WP_079281501.1 LysR substrate-binding domain-containing protein -
P9J59_RS00520 (P9J59_00520) 110058..110156 + 99 Protein_98 IS5/IS1182 family transposase -
P9J59_RS00525 (P9J59_00525) 110188..110295 - 108 Protein_99 transposase domain-containing protein -
P9J59_RS00530 (P9J59_00530) 110354..110617 - 264 WP_000203952.1 Txe/YoeB family addiction module toxin Toxin
P9J59_RS00535 (P9J59_00535) 110604..110867 - 264 WP_000557943.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
P9J59_RS00540 (P9J59_00540) 111283..114630 + 3348 WP_270893669.1 DEAD/DEAH box helicase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(8-87)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10664.10 Da        Isoelectric Point: 8.4894

>T276323 WP_000203952.1 NZ_CP121365:c110617-110354 [Acinetobacter baumannii]
MTSRNVEWTENAWDEYIYWQTQDKKILKRINTLIRECQRTPFEGTGKPEPLKANLSGFWSRRIDEKHRLVYEVTDERISI
IQCRFHY

Download         Length: 264 bp

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9841.04 Da        Isoelectric Point: 5.5940

>AT276323 WP_000557943.1 NZ_CP121365:c110867-110604 [Acinetobacter baumannii]
MHVFTYTDARNNLKSVLDKVIDDADVAFITRKEGGHAVVMGQDHYDSLMETLYLLSSPNNTTRLNESIAQLRAGKTKQRE
LIKDDES

Download         Length: 264 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2L2M0A2

Antitoxin

Source ID Structure
AlphaFold DB S7WSW9

References