Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 5505799..5506601 Replicon chromosome
Accession NZ_CP121355
Organism Mesorhizobium sp. WSM4906

Toxin (Protein)


Gene name TacT3 Uniprot ID -
Locus tag QAZ22_RS26770 Protein ID WP_278203759.1
Coordinates 5506074..5506601 (+) Length 176 a.a.

Antitoxin (Protein)


Gene name TacA3 Uniprot ID -
Locus tag QAZ22_RS26765 Protein ID WP_278203757.1
Coordinates 5505799..5506077 (+) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QAZ22_RS26750 (QAZ22_26750) 5501730..5502194 + 465 WP_278203751.1 NUDIX domain-containing protein -
QAZ22_RS26755 (QAZ22_26755) 5502203..5502955 - 753 WP_278203753.1 DNA repair protein RecO -
QAZ22_RS26760 (QAZ22_26760) 5503056..5505638 + 2583 WP_278203755.1 mechanosensitive ion channel -
QAZ22_RS26765 (QAZ22_26765) 5505799..5506077 + 279 WP_278203757.1 DUF1778 domain-containing protein Antitoxin
QAZ22_RS26770 (QAZ22_26770) 5506074..5506601 + 528 WP_278203759.1 GNAT family N-acetyltransferase Toxin
QAZ22_RS26775 (QAZ22_26775) 5506608..5507501 - 894 WP_278203761.1 aminoglycoside phosphotransferase family protein -
QAZ22_RS26780 (QAZ22_26780) 5507604..5508536 - 933 WP_278203763.1 GTPase Era -
QAZ22_RS26785 (QAZ22_26785) 5508521..5509237 - 717 WP_278077900.1 ribonuclease III -
QAZ22_RS26790 (QAZ22_26790) 5509242..5509991 - 750 WP_278077899.1 signal peptidase I -
QAZ22_RS26795 (QAZ22_26795) 5510072..5510485 - 414 WP_278077898.1 holo-ACP synthase -
QAZ22_RS26800 (QAZ22_26800) 5510482..5511069 - 588 WP_278203766.1 DUF2062 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Vibrio phage ICP1, Orf50

(11-87)


Sequences

Toxin        


Download         Length: 176 a.a.        Molecular weight: 18838.51 Da        Isoelectric Point: 8.7331

>T276290 WP_278203759.1 NZ_CP121355:5506074-5506601 [Mesorhizobium sp. WSM4906]
MTLPRWREEPISKSHDRASFDCGDEQMNDFLRRFARQSHEQNASKTFCGVDNANPDRVLGFYTIAPSAVAHEQVPAALTK
GLARHEVSGFKLARLATDLSVAGQGLGGQLLAAAALRCLRVAGEGGGLLFIIDAKSERAANWYRGYGAEPLSGKPLTLVM
PLATFAADLRAKGLL

Download         Length: 528 bp

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10330.11 Da        Isoelectric Point: 10.2441

>AT276290 WP_278203757.1 NZ_CP121355:5505799-5506077 [Mesorhizobium sp. WSM4906]
MSKPASDRTERFNIRIRPAQKAMIARAAALSHKDMTDFILDKVLPEAEAVIKAIEKTEVSERDFKRILELLEHPPKPNAK
LRAAIAALPDTI

Download         Length: 279 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References